2018
DOI: 10.1111/jtxs.12356
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Aging‐related changes in quantity and quality of saliva: Where do we stand in our understanding?

Abstract: The population has undergone a fundamental change in its age structure globally, with a rapid increase in elderly population. Innovation of tailored foods is still in its early stage to satisfy the needs of growing aging population. One of the biggest challenges in such food product development is lack of adequate understanding and characterization of endogenous factors, that is, age-related changes in saliva, which may influence oral processing of food and subsequently nutrient intake. Aging affects the saliv… Show more

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Cited by 185 publications
(170 citation statements)
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References 94 publications
(150 reference statements)
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“…Animal models [426] and in vitro and in vivo clinical models were developed [415,427]. The importance of saliva in oral tribology was also increasingly recognized, including changes in saliva due to age [428], dry mouth, and in vitro simulation system [429], effect of palm oil [430], and bio-lubricants [167]. It is interesting to note a wide perspective in the area of oral tribology, from dietary, evolutionary, archeological, ecological, and paleontological points of view [384, 385, 431−436].…”
Section: Oral Tribologymentioning
confidence: 99%
“…Animal models [426] and in vitro and in vivo clinical models were developed [415,427]. The importance of saliva in oral tribology was also increasingly recognized, including changes in saliva due to age [428], dry mouth, and in vitro simulation system [429], effect of palm oil [430], and bio-lubricants [167]. It is interesting to note a wide perspective in the area of oral tribology, from dietary, evolutionary, archeological, ecological, and paleontological points of view [384, 385, 431−436].…”
Section: Oral Tribologymentioning
confidence: 99%
“…Saliva is pivotal for bolus formation and consequently is also related to the sensory and textural experience. Xerostomia is a clinical condition characterized by an excessive sensation of dryness in the mouth, which is not necessarily linked to salivary gland hypofunction [30,44]. Xerostomia is estimated to affect 25-50% of older individuals [45].…”
Section: Dry Mouthmentioning
confidence: 99%
“…Specifically, PROP tasters and supertasters had a higher response than non-tasters. Interindividual differences in both the quantity and quality of saliva is also an interesting area here, especially as far as it affects astringency (e.g., Taladrid, Lorente, Bartolomé, Moreno-Arribas, & Laguna, 2019;Xu, Laguna, & Sarkar, 2019).…”
Section: Problems With the Cross-sectional Approach To Studying Percementioning
confidence: 99%