Aging of the vestibular system and its relationship to dementia

Smith, Paul F.

doi:10.1097/wco.0000000000001231

Cited by 2 publications

(2 citation statements)

References 43 publications

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“…Bilateral hearing loss is important because vestibular dysfunction, especially in older adults, is commonly associated with age-related hearing loss. This would suggest that hypoacusis may also contribute to cognitive deficits in these cases and that they are not exclusively due to vestibular dysfunction or aging ( Smith, 2021 , 2023 ). Some work has been done to control for both variables.…”

Section: Methodsmentioning

confidence: 99%

Vestibular dysfunction and its association with cognitive impairment and dementia

Aedo-Sanchez,

Riquelme-Contreras,

Henríquez

et al. 2024

Front. Neurosci.

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The vestibular system plays an important role in maintaining balance and posture. It also contributes to vertical perception, body awareness and spatial navigation. In addition to its sensory function, the vestibular system has direct connections to key areas responsible for higher cognitive functions, such as the prefrontal cortex, insula and hippocampus. Several studies have reported that vestibular dysfunction, in particular bilateral vestibulopathy, is associated with an increased risk of cognitive impairment and the development of dementias such as Alzheimer’s disease. However, it is still controversial whether there is a causal relationship between vestibular damage and cognitive dysfunction. In this mini-review, we will explore the relationship between the vestibular system, cognitive dysfunction and dementia, hypotheses about the hypothesis and causes that may explain this phenomenon and also some potential confounders that may also lead to cognitive impairment. We will also review multimodal neuroimaging approaches that have investigated structural and functional effects on the cortico-vestibular network and finally, describe some approaches to the management of patients with vestibular damage who have shown some cognitive impairment.

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Section: Methodsmentioning

confidence: 99%

Vestibular dysfunction and its association with cognitive impairment and dementia

Aedo-Sanchez,

Riquelme-Contreras,

Henríquez

et al. 2024

Front. Neurosci.

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“…Vestibular perception is particularly important for older adults. Age-related vestibular decline is associated with cognitive impairment, an increased risk of dementia (Smith, 2023), and an increased risk of falling (Montero-Odasso et al, 2022;WHO, 2021). The rate of fall-related death or serious injury is highest in people over 60 years of age.…”

Section: Introductionmentioning

confidence: 99%

Vestibular perceptual learning improves self-motion perception, posture, and gait in older adults

Fitze,

Ertl,

Radlinger

et al. 2024

Preprint

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Vestibular motion perception declines with age, increasing the risk of falling substantially. We performed a two-week perceptual learning intervention using a self-motion direction discrimination task (2800 training trials per person) on a 6DOF motion platform in healthy older adults (n=40, aged 70-88yr). Linear inter-aural and angular roll tilt vestibular thresholds improved with training (95\% credible interval for pre/post difference), suggesting altered sensitivity post-training. Moreover, improved perceptual abilities transfer to actual posture (reduced sway) and gait parameters. Passive self-motion discrimination training provides a new and promising way to counteract age-related sensory decline. It can reduce the risk of falling, and thereby maintain individual autonomy and quality of life.

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Aging of the vestibular system and its relationship to dementia

Cited by 2 publications

References 43 publications

Vestibular dysfunction and its association with cognitive impairment and dementia

Vestibular dysfunction and its association with cognitive impairment and dementia

Vestibular perceptual learning improves self-motion perception, posture, and gait in older adults

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