Aging in a Relativistic Biological Space-Time

Abstract

Here we present a theoretical and mathematical perspective on the process of aging. We extend the concepts of physical space and time to an abstract, mathematically-defined space, which we associate with a concept of “biological space-time” in which biological dynamics may be represented. We hypothesize that biological dynamics, represented as trajectories in biological space-time, may be used to model and study different rates of biological aging. As a consequence of this hypothesis, we show how dilation or contraction of time analogous to relativistic corrections of physical time resulting from accelerated or decelerated biological dynamics may be used to study precipitous or protracted aging. We show specific examples of how these principles may be used to model different rates of aging, with an emphasis on cancer in aging. We discuss how this theory may be tested or falsified, as well as novel concepts and implications of this theory that may improve our interpretation of biological aging.

The Frailty Puzzle: Searching for Immortality or for Knowledge Survival?

“…Studying time-related frailty biomarkers imposes another set of considerations. Maestrini et al (2018) suggest that relativistic corrections of physical time similar to those used in the Einstein relativistic theory resulting from accelerated or decelerated biological dynamics may be used to model the pace of aging. Such theoretical framework places and describes the biological dynamics as trajectories in a biological space-time reference system.…”

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“…62 In recent times, the old Newtonian notions of time in biological processes has been replaced with a more complex model that makes allowances for time dilatation and contraction. 63 Some authors suggest that biological aging is a manifestation of the cumulative of repetitions of certain cycles, for example circadian rhythms. Given the sheer number of such cycles occurring within a complex unit such as the midface, we face a reality in which, much like the quantum world, everything is changing all the time.…”

DIY Time Machine

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