Aging and recurrent urinary tract infections are associated with bladder dysfunction in type 2 diabetes

Abstract

The urodynamic study revealed a temporal effect on bladder function, and women with diabetic voiding dysfunction were found to have had a longer duration of DM than women with an overactive detrusor. However, aging and recurrent urinary tract infections are the two independent factors that contribute to impaired voiding function and diabetic bladder dysfunction.

Nocturia indicates a poor health status and increases mortality in male patients with type 2 diabetes mellitus

“…It is estimated that 382 million people (prevalence 8.3 %) had diabetes in 2013, and is expected to rise to 592 million by 2035 [1]. The prevalence of DM is about 4.9-9.2 % in Taiwan [2] and has increased steadily over the past decade [3]. Nocturia is a common condition in diabetic patients with an odds ratio ranging from 1.67 to 2.73 [4,5].…”

Hospitalization of elderly diabetic patients: characteristics, reasons for admission, and gender differences

“…Several factors are thought to predispose to urinary tract infections in diabetic patients, including older age, history of urinary tract infections, a longer history of diabetes, and increased HbA1c levels [30, 37]. The range of patient signs and symptoms can vary from classic to atypical in elderly patients [38].…”

“…The range of patient signs and symptoms can vary from classic to atypical in elderly patients [38]. In the elderly population with diabetes, autonomic neuropathy can reduce sensitivity and alter distensibility of the urinary bladder, leading to recurrent urinary tract infections or asymptomatic bacteriuria [30, 39]. Moreover, glycosuria enhances bacterial growth and impairs phagocytosis, which probably has a role in the increased incidence of urinary tract infections in diabetic patients, especially in the elderly.…”

Abdominal strength in voiding cystometry: a risk factor for recurrent urinary tract infections in women

“…The influence of lower urinary tract dysfunction (LUTD) on recurrent urinary tract infections in women is not clear [5]. Lin et al [6] found an association in diabetic women between recurrent urinary tract infections and urinary disorders (i.e., urinary stress incontinence, detrusor overactivity, increased bladder sensation, and impaired bladder function). However, in all these transversal studies of women with rUTIs there was no control group.…”