Aging and putative frailty biomarkers are altered by spaceflight
Andrea Camera,
Marshall Tabetah,
Veronica Castañeda
et al.
Abstract:Human space exploration poses inherent risks to astronauts’ health, leading to molecular changes that can significantly impact their well-being. These alterations encompass genomic instability, mitochondrial dysfunction, increased inflammation, homeostatic dysregulation, and various epigenomic changes. Remarkably, these changes bear similarities to those observed during the aging process on Earth. However, our understanding of the connection between these molecular shifts and disease development in space remai… Show more
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