Aggressive Fibromatosis: MRI Features with Pathologic Correlation

Abstract

Accurate diagnosis and staging of aggressive fibromatosis by MRI have important treatment and prognostic implications.

Imaging features of aggressive fibromatosis in psoas muscle

“…Although most cases of AF occur in a sporadic form, a minority is associated with some familiar neoplastic syndromes, such as familial adenomatous polyposis (FAP). Gardner's syndrome, a variant of FAP, is characterized by polyposis, osteoma and various soft tissue findings but can offer us several additional specific characteristics, including (a) bands with low signal intensity across all pulse sequences in lesion, (b) infiltrative growth pattern, (c) crossing fascial boundaries, and (d) no necrosis, fat and calcification inside the tumor, which could help radiologists recognize this entity and make a diagnosis (2,8). It is very uncommon that calcifications may be present and influence the signal of the tumor (9).…”

“…It is very uncommon that calcifications may be present and influence the signal of the tumor (9). Though Lee thought that the first characteristic was nonspecific because it occurred only in 10% cases, it reached a consensus that the remaining three were the typical manifestations of AF (2,8). This may indicate MRI could play an irreplaceable and crucial role in diagnosing AF of rare origin.…”

“…It shows characteristic infiltrative growth features and has a tendency for local recurrence (1). Due to low incidence, only a small number of cases of AF in extremities or in other locations have been reported (1)(2)(3). To the best of our knowledge, there is no previous report concerning the CT or MRI features of AF in psoas in the medical literature.…”

Posttraumatic Fibromatosis on the Chest Wall: A Case Report

“…Metastaz yapmaması, ancak lokal invazyon ve nüks görülebilmesi nedeniyle benign fibröz lezyonlar ile fibrosarkomlar arasında bir biyolojik davranış gösterirler. Genellikle kadınlarda ve hayatın 3.-4. dekatlarında daha sık görülür (2). Etyolojisi henüz net olmamasına karşın, travma, geçirilmiş operasyonlar, hormonal ve genetik nedenler sorumlu tutulmaktadır (3).…”

Diagnosis and multidisciplinary treatment of sporadical desmoid tumors

“…The incidence of desmoids in FAP patients is approximately 850 to 1000 times that of the general population and was 29% in the original Gardner kindred (11,14,15). The sporadic types are more common in women than in men with a ratio between 1.8 : 1 and 5 : 1 (5,9,16,17).…”