Aggressive Cutaneous Squamous Cell Carcinoma as an Adult Manifestation of Incontinentia Pigmenti

Abstract

}.Our observations suggest that COVID-19 has interrupted the skin cancer awareness campaigns that are crucial for boosting population awareness of melanoma. Although we had posited that COVID-19 disrupted a pattern of increased community engagement and thus concern for skin cancer in the warmer months, we were able to eliminate temperature-related variables as significant contributors to this observed phenomenon because search volumes in both the United States and Australia, countries that differ significantly in seasonal temperature patterns, experienced significant decreases. However, our findings are limited because Google Trends data only reflect the population with access to the internet. Regardless, it is important to be mindful of the reduction in public awareness campaigns because reduced population awareness of melanoma may lead to significant increases in the number of delayed diagnoses in the coming year.

Case report: Variability in clinical manifestations within a family with incontinentia pigmenti

“…In most cases, skin lesions disappear completely with age. Nevertheless, benign (subungual tumors) and malignant skin neoplasms may develop in individual cases ( 10 – 13 ). In our case, P was diagnosed with SCC on the skin of the right leg at the age of 10 years.…”

“…A rather rare event in IP is painful subungual tumors, which usually manifest after puberty ( 10 ). Single cases of multiple aggressive subungual SCC or SCC arising on the skin of patients with IP have also been described, mainly in adult patients ( 11 – 13 ). In this report, we presented a family with four cases of IP (mother and her three daughters) with very rare manifestation of the disease, SCC developing on the shin of the eldest daughter at the age of 10 years.…”