Aggressive conservative treatment of esophageal perforations in children

Tratamento das estenoses esofágicas por dilatação endoscópica em crianças e adolescentes

“…In our patient population, we decided to manage patients on an individual basis, and we used the Esophageal perforation is the most dreaded complication of endoscopic dilatation, with an incidence of 0.7 to 3.5%, and is always regarded as a severe clinical condition. 1,2,4,7,27 In our assessment of 869 dilatations, we had five cases of esophageal perforation (0.7%), which is in agreement with the literature. Early diagnosis of esophageal perforation with quick implementation of treatment is the most important prognostic factor for reducing morbidity and mortality among these patients.…”

“…Early diagnosis of esophageal perforation with quick implementation of treatment is the most important prognostic factor for reducing morbidity and mortality among these patients. 27 The conservative treatment of esophageal perforation with antibiotics, fasting, total parenteral nutrition, and intensive clinical monitoring is the method of choice for treating pediatric patients, resulting in a high survival rate and in organ preservation. 27 Other endoscopic treatments for esophageal stricture that the health professionals attending to these patients receive qualified training at referral centers and be able to improve their skills in pediatric endoscopy, always bearing in mind the peculiarities of childhood disorders and their treatment.…”

“…27 The conservative treatment of esophageal perforation with antibiotics, fasting, total parenteral nutrition, and intensive clinical monitoring is the method of choice for treating pediatric patients, resulting in a high survival rate and in organ preservation. 27 Other endoscopic treatments for esophageal stricture that the health professionals attending to these patients receive qualified training at referral centers and be able to improve their skills in pediatric endoscopy, always bearing in mind the peculiarities of childhood disorders and their treatment. 30 However, despite the current improvements in digestive endoscopy, prevention is still the best treatment …”

The Effects of Ankaferd Blood Stopper on the Recovery Process in an Experimental Oesophageal Perforation Model

“…This is achieved by administering broad-spectrum antibiotics, performing nasopharyngeal aspirations, ensuring sufficient pleural drainage, admitting patients to intensive care units, and maintaining adequate nutrition (5,8,15,16). However, major primary repair, resection, and anastomosis surgical procedures are frequently performed.…”

“…Locoregional complications, such as anastomotic leakage, wound infection, pleural effusion, mediastinitis, bleeding, and systemic complications, such as sepsis and multiple organ dysfunction syndrome (MODS), lead to high morbidity and mortality rates (4,5,7,8).…”