Aggressive Chondroid Syringoma

Botha, J. B. C.

doi:10.1001/archderm.1978.01640180086024

Cited by 19 publications

(6 citation statements)

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“…In contrast, the malignant transformation of a PA of the ear canal has been reported only by Botha and Kahn, as ‘aggressive chondroid syringoma’ [7]. Chondroid syringoma is the term used in dermatological practice to describe PA from skin appendages [7,8].…”

Section: Discussionmentioning

confidence: 99%

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Pleomorphic adenoma presenting with conductive hearing loss in the ear canal: a case report and review of the literature

2014

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IntroductionPleomorphic adenoma accounts for 65 percent of all salivary gland tumors. It has been identified in several anatomical regions, but pleomorphic adenoma arising in the ear canal, first described in 1951, is extremely rare.Case presentationA 40-year-old Japanese man’s left ear canal was obstructed by a pleomorphic adenoma that caused mild conductive hearing loss. The tumor was resected and he remains disease-free two years after surgery.ConclusionsPleomorphic adenoma usually arises from a major and minor salivary gland, but pleomorphic adenoma of the ear canal is derived from the ceruminous gland. We discuss the present case and 37 other case reports in our effort to clarify the clinical features and the course of pleomorphic adenoma in the ear canal.

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Section: Discussionmentioning

confidence: 99%

“…Chondroid syringoma is the term used in dermatological practice to describe PA from skin appendages [7,8]. In that case, the tumor recurred with cellular atypism and mitotic activity and accompanied several satellite nodules three years after the first resection [7]. Another case of recurrence was reported by Pahor et al .…”

Section: Discussionmentioning

confidence: 99%

Pleomorphic adenoma presenting with conductive hearing loss in the ear canal: a case report and review of the literature

2014

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“…However, we have been unable to find any report of a reliably diagnosed, completely excised adenoma which has recurred or spread. It should be mentioned here that one case of an 'aggressive chondroid syringoma' has been described (Botha and Kahn, 1978). (The term 'chondroid syringoma' or 'mixed tumour of the skin' is used in dermatological practice to describe tumours, identical to pleomorphic adeno-mas, arising in skin appendages).…”

Section: Behaviourmentioning

confidence: 99%

Ceruminous gland tumours: a reappraisal

1992

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Ceruminous glands should no longer be regarded as purely apocrine glands, but as apoeccrine glands with both apocrine and eccrine modes of secretion. We present two cases of pleomorphic adenoma of ceruminous glands, among the rarest of such tumours. The use of such terms as ‘ceruminoma’ and ‘hidradenoma’ should finally be abandoned, and ‘ceruminous gland tumour’ used instead as a generic term. Classification should be based on Wetli's prototype (adenoma, pleomorphic adenoma, adenoid cystic carcinoma and adenocarcinoma), with the addition of benign eccrine cylindroma and syringocystadenoma papilliferum; the inclusion of mucoepidermoid carcinoma should await full validation. Wide local excision is necessary for all tumours, with only follow-up for histologically benign neoplasms. Malignant tumours need early aggressive surgery and radiotherapy. If marginal invasion cannot be assessed histologically, then adenoma and adenocarcinoma cannot be distinguished and we suggest that the tumour be reported as ‘of uncertain malignant potential’. Long-term studies are needed to confirm or refute the view that all ceruminous gland tumours are potentially malignant.

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“…Nevertheless, a malignant transformation has been found in sporadic instances. Botha et al (16) published their study of a fifteen-year-old girl with a lesion in the external acoustic meatus which was removed and recurred three years later. The biopsy specimens taken both times showed the typical aspect of chondroid syringoma.…”

Section: Course and Prognosismentioning

confidence: 99%