Aggressive Angiomyxoma of Vulva Which Grew with Pregnancy and Attained a Huge Size Rarely Seen in Literature

Sinha, Vandana; Dave, Kalpana; Bhansali, Ronak P.; Arora, Ruchi

doi:10.1007/s13224-012-0338-2

Cited by 6 publications

(7 citation statements)

References 2 publications

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“…The first case of AA in pregnancy was reported in 1995, and only 16 cases have been reported in pregnancy to date ( Table 1 ). 2 – 15 The cause of AA is unknown. Our case was similar to most cases of AA in pregnancy.…”

Section: Discussionmentioning

confidence: 99%

Aggressive angiomyxoma in pregnancy: a case report and literature review

Sun

et al. 2020

J Int Med Res

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Aggressive angiomyxoma is an interstitial tumour that is often misdiagnosed and is likely to recur. There have been few reported cases of angiomyxoma in pregnant women. We report a case of a woman who was previously diagnosed with a tumour in her vulva that increased in size during both of her pregnancies and spontaneously decreased postpartum. Local excision was performed and a gonadotropin-releasing hormone agonist was administered. According to a literature review, aggressive angiomyxoma is associated with good maternal and child outcomes. Caesarean section is not the delivery method of choice, but it is indicated if the tumour is preventing vaginal birth. Treatment for angiomyxoma is mainly postpartum local resection supplemented by hormone therapy. This tumour frequently recurs and patients should undergo long-term follow-up.

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Section: Discussionmentioning

confidence: 99%

Aggressive angiomyxoma in pregnancy: a case report and literature review

Sun

et al. 2020

J Int Med Res

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“…Diffusion-weighted imaging shows uneven, slightly high signal shadows [ 25 ]. In some older cases (published more than 10 years ago), computed tomography (CT) was used in the postpartum period, but it never highlighting distant locations [ 17 , 18 , 20 ].…”

Section: Resultsmentioning

confidence: 99%

Aggressive Angiomyxoma of the Lower Female Genital Tract in Pregnancy: A Review of the MITO Rare Tumors Group

Cicogna

Dellino

Miano

et al. 2023

Cancers

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Deep (aggressive) angiomyxoma of the lower genital tract is a rare malignancy affecting women of reproductive age. Being a hormone-sensitive tumor, its growth is particularly benefitted during pregnancy. Surgical excision with complete resection is indicated, even if a wait-and-see approach can be considered until delivery, to avoid destructive surgeries. The mode of delivery is to be evaluated based on the location and size of the neoplasm; vaginal delivery is not contraindicated, as long as the tumor does not obstruct the birth canal. Positive surgical margins are the most important prognostic factor for recurrence. Adjuvant therapy with gonadotropin-releasing hormone analogues may be proposed after pregnancy, in the case of non-radical surgery. Despite the high local relapse rate, the outcomes for mother and child are favorable. Since recurrences can occur after many years, the patient should be included in long-term follow-up.

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“…The uniqueness of our work is not only for the analysis of the pathological management, but also for the presence of a complex, ongoing twin pregnancy and the observed sequelae of the treatment. To our knowledge, this is the most updated review on the topic [ 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 ]. The variety of the possible body locations, the association with pregnancy, and the few cases known in the literature make it difficult to formulate unique guidelines on this subject.…”

Section: Discussionmentioning

confidence: 99%

Aggressive Pelvic Angiomyxoma in a Patient with Twin Pregnancy: Diagnosis, Treatment, and Clinical Complications in Light of the Literature

Aquino

Tinelli²,

Libretti

et al. 2023

Medicina

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(1) Background: Aggressive angiomyxoma is a mesenchymal cancer that is rare during pregnancy. It is a neoplasm that relapses and infiltrates the nearest structures. Our aim is to evaluate the management and outcomes of an observed case, in light of the current literature. (2) Methods: We observed this condition at the “Maggiore della Carità” Hospital in Novara (Italy) in a patient with an initial twin pregnancy and a suspected pelvic mass. The words “angiomyxoma” and “pregnancy” were searched on the main online scientific search sources (PubMed, Google Scholar, Scopus, WES, and Embase, etc.). (3) Results: The patient underwent surgery with a complicated follow-up, but recent negative controls. We analyzed the literature about the topic and found only 24 similar clinical cases. (4) Conclusions: Considering the current literature, it is useful to assess an aggressive angiomyxoma in the differential diagnosis of soft masses in pregnant women. The treatment of choice is surgical excision, and vaginal delivery is feasible. The therapeutic decision depends on each case.

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Aggressive Angiomyxoma of Vulva Which Grew with Pregnancy and Attained a Huge Size Rarely Seen in Literature

Cited by 6 publications

References 2 publications

Aggressive angiomyxoma in pregnancy: a case report and literature review

Aggressive angiomyxoma in pregnancy: a case report and literature review

Aggressive Angiomyxoma of the Lower Female Genital Tract in Pregnancy: A Review of the MITO Rare Tumors Group

Aggressive Pelvic Angiomyxoma in a Patient with Twin Pregnancy: Diagnosis, Treatment, and Clinical Complications in Light of the Literature

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