Aggressive angiomyxoma of larynx: case report and literature review

Abstract

To our knowledge, this is the second report in the world literature of aggressive angiomyxoma of the larynx. Comparison with the female pelvic counterpart facilitates diagnosis, aided by recent advances, and suggests that complete surgical excision with a wide margin is the treatment of choice.

Case Report: Life-threatening angiomyxoma of the larynx

“…Angiomyxoma of the larynx is understood to be counterpart of these tumors ( 1 – 3 ). The presenting symptoms of larengeal angiomyxoma are similar to many of the larengeal masses, and these include dysphagia, dysphonia, dyspnea, cough, respiratory distress and obstructive sleep apnea ( 1 , 2 ). It may be caused by airway obstruction requiring emergency tracheotomy.…”

A rare case of aggressive angiomyxoma of vulva since childhood

“…High rates of angiomyxoma were reported in skeletal muscles. 5 Rare cases were reported in larynx, 6 lung, 7 maxillary sinus, 8 jejunum 9 and bladder. 10 In females it is common in the perineal and pelvic regions.…”

Aggressive angiomyxoma of the thigh: A case report and review of the literature

“…Histologically, the tumor was characterized by spindle and stellate cells in a loose myxoid stroma with a prominent vascular component (2). Immunohistochemical staining of the tumor, particularly the reactivity for desmin, α-smooth muscle actin, muscle-specific actin, vimentin, CD-34, S-100 protein, estrogen and progestin receptors, is essential for diagnosis (12,15,16).…”

“…AAM has also been described in the male larynx, genital tract and supraclavicular fossa (2)(3)(4). A notable case of AAM on the upper, lateral aspect of the right thigh in a male patient has also been reported (5).…”