Aggressive angiomyxoma: A clinicopathologic study of 29 female patients

Fetsch, John F.; Laskin, William B.; Lefkowitz, Martin; Kindblom, Lars‐Gunnar; Meis‐Kindblom, Jeanne M.

doi:10.1002/(sici)1097-0142(19960701)78:1<79::aid-cncr13>3.0.co;2-4

Cited by 312 publications

(264 citation statements)

References 39 publications

(3 reference statements)

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“…Recurrence is local and reported in 36 to 72%. 2 Radiotherapy and chemotherapy may not have much role due to the low mitotic activity seen. 1 GnRH agonist 3 and tamoxifen have been used successfully in few patients.…”

Section: Resultsmentioning

confidence: 99%

Aggressive Angiomyxoma Pelvis Presenting as an Ovarian Tumor with Vault Prolapse

Dhaliwal¹,

Aggarwal²,

Nijhawan³

et al. 2012

Journal of Postgraduate Medicine, Education and Research

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Section: Resultsmentioning

confidence: 99%

Aggressive Angiomyxoma Pelvis Presenting as an Ovarian Tumor with Vault Prolapse

Dhaliwal¹,

Aggarwal²,

Nijhawan³

et al. 2012

Journal of Postgraduate Medicine, Education and Research

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“…This tumor generally occurs as a large, slow growing, polypoid mass or ill defined swelling in the pelvic region with infiltrating margins. The tumor size varies between 3 and 60cm (Fetsch et al, 1996;Begin et al, 1985;White & Chan, 1994). Our case had an 11cm* 8 cm size mass in the right labial region.…”

Section: Discussionmentioning

confidence: 99%

“…Fetsch et al, reported a clinicopathological study of 29 female patients with pelvic and perineal Aggressive Angiomyxomas. They emphasized the importance of long term followup since the first evidence of recurrence may be many years after the initial resection (Fetsch et al, 1996). Our case is on regular followup for the past one year and is disease free till date.Radiation therapy was given for a case of recurrent Aggressive Angiomyoma which achieved local control by Suleiman et al (Suleiman et al, 2006).…”

Section: Discussionmentioning

confidence: 99%

“…It is known as Aggressive Angiomyxoma in view of the neoplastic nature of the blood vessels and locally infiltrative nature. Only few cases have been reported about this rare tumor in the world literature (Fetsch et al, 1996;Begin et al, 1985;White & Chan, 1994). Here we describe a rare case of rapidly growing vulval Aggressive Angiomyxoma in a young multiparous female.…”

Section: Introductionmentioning

confidence: 99%

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Rare Case of Aggressive Angiomyxoma of the Vulva: A Case Report

shanmugasundaram

Maharajan

2016

CCO

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Aggressive Angiomyxoma (AA) is a rare locally aggressive soft tissue tumor with high chance of local recurrence occuring in young women of reproductive age group. These neoplasms are characterized by a mixture of spindle or stellate cells in a loosely myxoid stroma with prominent vascular component containing large, thickwalled blood vessels. A 35 year old multiparous lady presented with right vulval swelling which was rapidly progressing in size. Local examination revealed a soft fleshy mass occupying whole of the right labia majora. In view of the rapidly enlarging lesion over a short duration, we suspected a soft tissue neoplasm and preceded with wide local excision of the mass with adequate margins in all dimensions, eventhough we did not have a preoperative tissue diagnosis. To our surprise, final histopathology was Aggressive Angiomyxoma (AA). The treatment of choice for Aggressive Angiomyxoma is wide local excision with negative margins and the same was done in our case. Recurrence of the tumor may be avoided by wide local excision with adequate margins. It is possibly a hormonally responsive neoplasm. Treatment with Gonadotropin-releasing hormone is an emerging therapy. Overall prognosis of AA is good.

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“…3 Because of the similar appearance with the lipoma, vaginal cysts and bartholin cysts and slow growth, AA is often diagnosed lately or misdiagnosed. Despite slowgrowth, AA could reach to a great size (up to 60 cm), but usually the largest diameter is about 10-20 cm.…”

Section: Discussionmentioning

confidence: 99%

Aggressive Angiomixoma of the Vulva: Case Report

Çakmak¹,

Metin²,

Köseoğlu³

et al. 2015

Turkiye Klinikleri J Case Rep

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A AB BS ST TR RA AC CT T Aggressive angiomyxoma (AA) is an uncommon mesenchymal tumour of epidermis with local recurrence and rare metastasis. AA is treated with total excision and often lately diagnosed or misdiagnosed because of slow growth and similar features as the lipoma, vaginal cysts and bartholin cysts. Total excision of AA is the main treatment and provides curative therapy. In this case report, we present a 38-year-old woman with a vulvar mass diagnosed as aggressive angiomyxoma and underwent total excision procedure.K Ke ey y W Wo or rd ds s: : Myxoma; vulva Ö ÖZ ZE ET T Agresif anjiyomiksoma (AA) nadir görülen, lokal rekürrens ve nadir metastaz özelliği olan benign mezenkimal tümör olup epidermis kökenlidir. AA'nın tedavisi total eksizyondur; yavaş bü-yümesi, lipom, bartholin kisti ve vajinal kistlerle benzer görünümde olması nedeniyle genellikle yanlış ya da geç tanı almaktadır. AA'nın gerçek tedavisi total eksizyon olup bu prosedür genellikle kür sağlamaktadır. Bu yazıda, 38 yaşında vulvadan köken alan ve histopatolojik olarak anjiomiksoma tanısı konulan ve total eksizyon yapılan bir olgu sunulmuştur.A An na ah ht ta ar r K Ke el li im me el le er r: : Miksoma; vulva T Tu ur rk ki iy ye e K Kl li in ni ik kl le er ri i J J C Ca as se e R Re ep p 2 20 01 15 5; ;2 23 3( (3 3)

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Aggressive angiomyxoma: A clinicopathologic study of 29 female patients

Abstract: BACKGROUND. Aggressive angiomyxoma is an uncommon mesenchymal tumor

Cited by 312 publications

References 39 publications

Aggressive Angiomyxoma Pelvis Presenting as an Ovarian Tumor with Vault Prolapse

Aggressive Angiomyxoma Pelvis Presenting as an Ovarian Tumor with Vault Prolapse

Rare Case of Aggressive Angiomyxoma of the Vulva: A Case Report

Aggressive Angiomixoma of the Vulva: Case Report

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