Aggregation Processes of a Weak Polyelectrolyte, Poly(allylamine) Hydrochloride

Abstract

Poly(allylamine) hydrochloride is a weak cationic polyelectrolyte that exhibits different aggregation properties at different solution pH values and aging times. Specifically, after several days aging in a pH 3 buffer, less than 1 mg/mL poly(allylamine) hydrochloride became turbid, and the hydrodynamic radius increased with a single diffusion mode. However, the hydrodynamic radius did not change at high concentrations. The dynamic processes of polymer aggregations at different pH values were verified by a light scattering and zeta-potential apparatus. The major interaction was caused by the capturing of counterions by the polyelectrolyte, which generates electrostatic, hydrophobic and cation-π interactions.

Polyphosphate Poly(amine) Nanoparticles: Self-Assembly, Thermodynamics, and Stability Studies

“…Polyamines interact with phosphate ions through electrostatic and hydrogen bonding − leading to supramolecular structures, where the phosphate ions link different polyamine chains together. , Colloidal particles , and thin films , can be easily fabricated through the complexation of polyamines and inorganic phosphates. Polyamine phosphate interactions have also been extensively applied for the complexation of nucleid acids for gene therapy applications .…”