Aggregation of polymeric polysaccharide-based nanoparticles as a challenge in microwave tomography targetting breast cancer

Comparison of the Antibacterial Activity of Selected Deep Eutectic Solvents (DESs) and Deep Eutectic Solvents Comprising Organic Acids (OA‐DESs) Toward Gram‐Positive and Gram‐Negative Species

“…One of the most important features of DESs, from the (bio)medical point-of-view, is the ability to enhance the effectiveness of therapeutics either by means of increased drug solubilization or by direct incorporation of the drug in the DES. [18] DESs have, in this manner, already been implemented to improve the administration of small-molecule drugs, such as ibuprofen, [19][20][21] aspirin, [22] acetaminophen, naproxen, benzoic acid, and phenylacetic acid. [23,24] In addition, DESs were tested as activity enhancers for already implemented antibiotics, such as clindamycin.…”

“…From the above literature data, it is obvious that most of the investigated DESs were usually tested only on a few strains and their antimicrobial activity was assessed usually only with one technique (either minimum inhibitory concentration or disk diffusion test); thus, limiting their adaptation perspective. Reviews in this topic have been recently published by us [ 18 ] as well as by Marchel et al. [ 33 ] In the latter one, the authors not only presented the antimicrobial results of different studies done throughout the years but also critically evaluated the methods used for assessment of antimicrobial potential of DESs, highlighting the limitations of different methods and need of standardized protocols that would allow for in‐depth microbiological analysis of the material.…”