Aggregation of petroporphyrins and fragmentation of porphyrin ions: Characterized by TIMS-TOF MS and FT-ICR MS

Evaluation and Characterization of Ultrathin Poly(3-hydroxybutyrate) Fibers Loaded with Tetraphenylporphyrin and Its Complexes with Fe(III) and Sn(IV)

“…Along with the bactericide activity, due to the specific geometry and electronic structure, the complexes of metals with porphyrins have a significant effect on the crystallization and segmental orientation of macromolecules [ 22 ]. The pristine porphyrin molecules as well as their metal complexes are amphiphilic [ 23 ] or even hydrophobic [ 24 ] that promote their aggregation in the form of nanoparticles [ 23 , 25 , 26 , 27 ]. Depending on the nature of the metal included in metalloporphyrins, they exhibit a variable tendency to aggregation [ 28 ] that determines their ability to act as nucleating agents during polymer crystallization.…”

Advances and Challenges in the Molecular Characterization of Petroporphyrins

“…For example, Zheng et al 23 combined positive-ion ESI with TIMS-TOF-MS to investigate petroporphyrin aggregates from porphyrin-enriched crude oil fractions. 49 TIMS-FT-ICR MS was first applied to the characterization of synthetic geologically relevant metalloporphyrins by Benigni et al, 50 51 Thus, for a specific core molecular structure, the extent of alkylation results in a linear change in CCS and can be used to estimate the CCS for putative petroporphyrin cores with no alkyl substituents. Finally, theoretical CCS determinations were conducted based on core structures and extrapolated to alkylated petroporphyrins based on the observed linear correlation between CCS and the degree of alkylation.…”

“…Zheng et al 176 characterized vanadyl porphyrins in heavy crude oil using ion mobility spectrometry. A series of mobiligram peak cluster ions was observed in the extracted ion mobility spectra of the porphyrins, which may contain an amine in the ions.…”

“…Experimental results from model compounds indicate that all porphyrins tend to form adduct ions in electrospray ionization, such as [2 M] + , [2 M + H] + , [2 M + Na] + and clusters of ions of porphyrin with other compounds.This result implies the strong molecular aggregation potential of porphyrins with themselves and other petroleum molecules. The results are instructive for understanding the structure of nonporphyrins, although much remains unknown 176. …”

Highly Purified Conjugates of Natural Chlorin with Cobalt Bis(dicarbollide) Nanoclusters for PDT and BNCT Therapy of Cancer

“…In this regard, the issue of the identification and isolation of target compounds in an individual state from the reaction mixture is relevant. Modern approaches to the identification of natural porphyrins and their derivatives are increasingly based on the use of high-performance liquid chromatography with high-resolution tandem mass spectrometry [ 15 , 16 ]. This method is also actively used in the analysis of porphyrins in various biological samples [ 17 , 18 ].…”