Aggregation Mechanisms in Pharmaceutical Suspensions

Orthokinetic Coagulation in Pharmaceutical Suspensions

“…The question of whether or not drug particles may be flocculated or coagulated in an analogous way to lyophobic colloids to prevent impaction on storage was discussed extensively in the literature (6,(13)(14)(15)(16)(17)(18). Because of the previously mentioned differences between lyophobic colloids and drug suspensions, it can be misleading to apply criteria derived from colloid chemistry to differentiate between aggregation mechanisms in coarse systems.…”