Aggregation‐Induced Emission: A Tool for Sensitive Detection of Amines

Abstract

The aggregation-induced emission (AIE) phenomenon has shown great potential to develop sensors for amine detection. The AIE-active fluorescent probes are free from the aggregation-caused fluorescence quenching, which is a major problem in the conventional fluorescent probes. The fluorescent aggregates formed by AIE strategy offer advantages such as high selectivity, sensitivity, low background interference as well as the simplicity of the fluorescence technique. This review aims to highlight the recent developments of AIE-active probes for the detection of amine derivatives. We will focus our discussion on the AIE concept to develop ''turn on'' and ''turnoff'' fluorescent sensors for the detection of amine derivatives. Thereafter, we will discuss the various examples of amine sensor with their detection mechanism. Finally, we will give a future perspective for the development of AIE-based amine sensors. We believe, this review will inspire scientists of this emerging world for the development of new amine sensors.

A Versatile AIE Fluorogen with Selective Reactivity to Primary Amines for Monitoring Amination, Protein Labeling and Mitochondrial Staining

“…29 Because AIEgens are highly luminescent in the solid-state, they are ideal candidates for such purpose. 30 Curiously, we further fabricated the spin-coating films of CMVMN from its dichloromethane solution and fumed it with PA vapors. As depicted in Figure 2f, after exposure to PA vapors for 1 min, a remarkable red-shift in the emission peak was observed.…”

A versatile AIE fluorogen with selective reactivity to primary amines for monitoring amination, protein labeling, and mitochondrial staining

“…[53,54] The strong emission of AIEgens in solid-state makes them ideal candidates for such purpose. [55] Curiously, the spin-coating films of CMVMN was fabricated from its dichloromethane solution and then fumed with PA vapors. A remarkable red-shift emission was observed 1 min later (Figure 2F).…”

A pyrylium salt-based fluorescent probe for the highly sensitive detection of methylamine vapour

“…The urge to overcome these problems has led to the development of fluorescence sensors due to their advantages of high selectivity, simplicity, real-time spatial imaging and nondestructivity. [18][19][20][21][22][23] The design and synthesis of fluorescent dyes are essential to fluorescence molecular imaging, and much effort has been exerted to exploit new dyes. For practical application, it is preferable to use easily fabricated solid-state fluorescent sensors as they are portable, offer convenient operation and do not need complex and expensive instruments.…”