Agents-induced nephrotoxicity and catcheins

Abstract

The present review was performed to gather the available literature on the nephroprotective effects of catechins against toxic agents. Several studies have demonstrated the therapeutic effects of catechins versus nephrotoxic agents such as cisplatin, cyclosporine A, tamoxifen, FK506, gentamicin, ethylene glycol, calcium, oxalate monohydrate, cadmium, ferric nitrilotriacetate, hydrogen peroxide, contrast medium, fructose, glucose, melamine vanadium, ochratoxin A, streptozotocin. However, more investigations should be done to indicate the nephroprotective effects of catechins against toxic agents in humans.