2009
DOI: 10.1186/1757-1627-2-6640
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Agenesis of isthmus of thyroid gland in adult human cadavers: a case series

Abstract: The thyroid gland, a highly vascular endocrine gland, is composed of two lateral lobes connected by a narrow median isthmus thus giving an 'H' shaped appearance to the gland. A wide range of morphological variations and developmental anomalies of the thyroid gland have been reported in the literature. In our study, on the morphometric features of the thyroid gland it was found that, 6 out of 41 thyroid glands that were dissected, showed an absence of the isthmus. The respective lateral lobes were positioned in… Show more

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Cited by 9 publications
(15 citation statements)
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“…Agenesis of isthmus of thyroid gland is rare in humans, the incidence varying from 5% to 10 %. 7 In our study incidence of absence of isthmus is in 9% (8 specimens), out of which 5 were male specimens & 3 were female specimens. This observation can be compared with studies done by Marshall The isthmus may be missing in the amphibians, birds and among mammals -monotremes, certain marsupials, cetaceans, carnivores and rodents.…”
Section: Discussionmentioning
confidence: 46%
See 1 more Smart Citation
“…Agenesis of isthmus of thyroid gland is rare in humans, the incidence varying from 5% to 10 %. 7 In our study incidence of absence of isthmus is in 9% (8 specimens), out of which 5 were male specimens & 3 were female specimens. This observation can be compared with studies done by Marshall The isthmus may be missing in the amphibians, birds and among mammals -monotremes, certain marsupials, cetaceans, carnivores and rodents.…”
Section: Discussionmentioning
confidence: 46%
“…6 Agenesis of isthmus can be associated with other types of dysorganogenesis, such as the absence of a lobe or presence of ectopic thyroid tissue & hence in clinical practice when such a condition is diagnosed, it is necessary to perform a differential diagnosis against other pathologies such as autonomous thyroid nodule, thyroiditis and so on. 7 While planning for thyroidectomy one should be prepared to find variations like ectopic thyroid nodules around normally located thyroid gland.…”
Section: Resultsmentioning
confidence: 99%
“…and anteroposterior extent being 3 cm and 2 cm respectively. The isthmus measures about 1.25 cm transversely as well as vertically and is usually placed anterior to the second and third tracheal cartilages [2]. Most of the diseases affecting the thyroid gland e.g.…”
Section: Introductionmentioning
confidence: 99%
“…The anomalies of the development Developmentally, the first endocrine gland in the embryo is the thyroid gland [1]. It is highly vascular endocrine gland composed of two lateral lobes connected by a narrow median isthmus giving an 'H' shaped appearance to the gland [2]. A wide range of multiple morphological variations and developmental anomalies of the thyroid gland have been reported in the literature [3].…”
Section: International Journal Of Anatomy and Research Int J Anat Rementioning
confidence: 99%