Agenesia de segmento infra-hepático de veia cava inferior associada a trombose venosa profunda de repetição: relato de caso

Grillo, Vinicius Tadeu Ramos da Silva; Filho, Pedro Luciano Mellucci; Jaldin, Rodrigo Gibin; Bertanha, Matheus; Pimenta, Rafael Elias Fares; Sobreira, Marcone Lima

doi:10.1590/1677-5449.210006

Cited by 6 publications

(1 citation statement)

References 13 publications

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“…Деякі літературні джерела говорять про двосторонній розвиток тромботичного процесу у венах нижніх кінцівок у пацієнтів з аномаліями розвитку НПВ (так звані білатеральні венозні тромбози) [4,10].…”

Section: результати обговоренняunclassified

Features of treatment of venous thromboembolism in patients with abnormalities in the development of the vena cava inferior

Khrebtiy¹

2023

Rep. of Vinnytsia Nation. Med. Univ.

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Annotation. In the treatment of venous thromboembolism, a special place is occupied by patients with congenital anomalies of the development of the inferior vena cava (IVC). To date, only single cases of treatment of this pathology have been described in the literature. Studying the experience of treating patients with congenital anomalies of the IVC will allow to improve the results of treatment of this category of patients. We analyzed the results of treatment of 1243 patients with venous thromboembolism from 2010 to 2022. For the diagnosis of venous thromboembolism, we used duplex scanning of the veins of the lower extremities, phlebography by spiral computed tomography (SCT), angiopulmonography, and phlebography. 32 (2.5%) patients had bilateral thrombosis of the ileofemoral venous segment. Congenital anomalies of IVC development were diagnosed in 2 (0.16%) patients. One patient had IVC aplasia, the other had IVC hypoplasia. Both patients had bilateral ileofemoral phlebothrombosis. For the treatment of patients with congenital anomalies of IVC and bilateral ileofemoral deep vein thrombosis, we used anticoagulant therapy and elastic compression of the lower extremities. During the study period, venous thromboembolic complications in the form of pulmonary embolism were not recorded, fatal complications were not diagnosed. Massive bleeding was not diagnosed in this category of patients during the study period. Thus, the conducted analysis allows us to state that the use of anticoagulant therapy allows to obtain satisfactory results of treatment of patients with congenital abnormalities of the development of the IVC.

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Section: результати обговоренняunclassified

Features of treatment of venous thromboembolism in patients with abnormalities in the development of the vena cava inferior

Khrebtiy¹

2023

Rep. of Vinnytsia Nation. Med. Univ.

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Infrarenal inferior vena cava agenesis presenting as acute abdomen and hydronephrosis – case report

Brkić

Želalić

Zekan-Vučetić

et al. 2023

Radiology Case Reports

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Direct Oral Anticoagulants for Inferior Vena Cava Agenesis

Iarossi,

Hermans

2023

Clin Appl Thromb Hemost

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Deep vein thrombosis (DVT) is common in the general population, with an annual incidence of 1 to 2 per 1000 people. Inferior vena cava agenesis (IVCA) increased the risk of developing DVT and is found in approximately 5% of young adults (20-40-year-olds) diagnosed with unprovoked proximal DVT. IVCA can be caused by a defective embryological process, or be a result of intrauterine or perinatal thrombosis. Its estimated incidence in the general population ranges from 0.0005% to 1%, usually involving a partial absence of one of the four segments of the inferior vena cava (IVC). The management during the extended phase of patients with DVT associated with IVCA is not yet harmonized, as it is poorly described in the literature. Patients with IVCA are considered to be at high risk of DVT occurrence, prompting physicians to continue extended anticoagulation, often using vitamin K antagonists. In this retrospective study, we present a cohort of 11 patients diagnosed with IVCA following a DVT, who subsequently received extended treatment with a direct oral anticoagulants. These findings offer reassuring insights into the extended utilization of direct oral anticoagulants, demonstrating both antithrombotic efficacy and a favorable safety profile.

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Agenesia de segmento infra-hepático de veia cava inferior associada a trombose venosa profunda de repetição: relato de caso

Cited by 6 publications

References 13 publications

Features of treatment of venous thromboembolism in patients with abnormalities in the development of the vena cava inferior

Features of treatment of venous thromboembolism in patients with abnormalities in the development of the vena cava inferior

Infrarenal inferior vena cava agenesis presenting as acute abdomen and hydronephrosis – case report

Direct Oral Anticoagulants for Inferior Vena Cava Agenesis

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