Ageing with cerebral palsy: psychosocial issues

Horsman, M.D. Klein; Suto, Melinda; Dudgeon, Brian J.; Harris, Susanna

doi:10.1093/ageing/afq018

Cited by 30 publications

(18 citation statements)

References 17 publications

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“…This tool has also been used in several recent systematic reviews [57][58][59]. The tool is not designed to produce a summary score that can quantify the quality of an article.…”

Section: Quality Assessment Proceduresmentioning

confidence: 99%

Leaders’ experiences and perceptions implementing activity-based funding and pay-for-performance hospital funding models: A systematic review

et al. 2015

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“…This tool has also been used in several recent systematic reviews [57][58][59]. The tool is not designed to produce a summary score that can quantify the quality of an article.…”

Section: Quality Assessment Proceduresmentioning

confidence: 99%

Leaders’ experiences and perceptions implementing activity-based funding and pay-for-performance hospital funding models: A systematic review

et al. 2015

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“…It is caused by damage or injury to one or more specific areas of the brain that occurs during fetal development, the perinatal period, or infancy . While CP is traditionally considered a childhood disorder, in reality it is a lifelong condition that presents challenges at every stage of development …”

mentioning

confidence: 99%

“…The GMFCS is an observational tool that categorizes an individual's motor function level by a 5‐point severity scale, where level I represents a person who has the ability to walk without limitations, levels II and III represent people with walking limitations, and levels IV and V represent individuals who require wheeled mobility most or all of the time . When a person with CP loses their ability to walk independently (GMFCS levels IV or V), sedentary behaviors, obesity, sarcopenia, and increased frailty may become apparent …”

mentioning

confidence: 99%

“…1 While CP is traditionally considered a childhood disorder, in reality it is a lifelong condition that presents challenges at every stage of development. 2 In recent years, there has been growing evidence that young adults with CP can develop a variety of secondary health conditions that typically occur later in life. [1][2][3] Adults with CP have an increased risk of excessive adipose tissue deposition insulin resistance, 4 sarcopenia, 4 and for developing cardiovascular disease (CVD), compared to the general population.…”

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confidence: 99%

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Prevalence of metabolic syndrome and cardiovascular disease risk factors in adults with cerebral palsy

Heyn

Tagawa

Pan

et al. 2019

Develop Med Child Neuro

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Aim To investigate the prevalence of metabolic syndrome and cardiovascular disease (CVD) risk factors and the association between common metabolic markers and Gross Motor Function Classification System (GMFCS) levels in ambulatory adults with cerebral palsy (CP). Method Metabolic markers and GMFCS levels were evaluated in a cross‐sectional study of 70 ambulatory adults with CP (34 males, 36 females; mean age 24y 5mo [SD 5y 4mo], range 18y 6mo–48y 8mo) to determine the prevalence of metabolic syndrome and CVD risk factors, and were compared to age‐matched, population norms from the National Health and Nutrition Examination Survey (NHANES) registry. The Framingham Heart Study (FHS) CVD risk estimation was also used to evaluate an individual's risk for CVD. Results Metabolic syndrome was identified in 17.1% of the cohort, higher than the 10% in the NHANES registry. The FHS CVD 30‐year lipid and body mass index (BMI)‐based risk factor results showed that 20% to 40% of the cohort was at greater risk of developing CVD (BMI‐based: 39.7% ‘full’ CVD risk factor; lipid‐based: 26.5% ‘full’ CVD risk factor) as compared to the FHS normative population data. There was a positive correlation between GMFCS level, waist circumference (r=0.28, p=0.02), and waist‐to‐hip ratio (r=0.28, p=0.02). Interpretation Adults with CP are at higher risk of CVD and metabolic syndrome compared to the general population, which is probably because of impaired mobility. What this paper adds Gross Motor Function Classification System levels can predict cardiovascular disease (CVD) risk factors in adults with cerebral palsy (CP). Anthropometric measures are significant in predicting CVD risk factors in adults with CP. Early CVD screening and ongoing risk factor monitoring are important in adults with CP.

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“…The motor disorders of cerebral palsy are often accompanied by disturbances of sensation, perception, cognition, communication, and behavior, or by epilepsy and secondary musculoskeletal problems (Horsman et al ., 2010). While in certain cases there is no identifiable cause, other etiologies include problems in intrauterine development ( e.g.…”

Section: Serious Neurodevelopmental Disordersmentioning

confidence: 99%

Neurobehavioral manifestations of developmental impairment of the brain

Dubovický¹

2010

Interdisciplinary Toxicology

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Individual characteristics of human nature (e.g. introversion, extroversion, mood, activity, adaptability, aggressiveness, social ability, anxiety) do not need to be primarily innate. They can be determined by the action of various influences and their interactions on functional development of the brain. There is ample epidemiological and experimental evidence that chemical and/or physical factors acting during sensitive time windows of the brain development can cause mental, behavioral, emotional and/or cognitive disorders. Environmental pollutants, addictive substances, drugs, malnutrition, excessive stress and/or hypoxia-ischemia were reported to induce functional maldevelopment of the brain with consequent neurobehavioral disorders. The article provides review on most significant neurobehavioral manifestations of developmental impairment of the brain during prenatal, perinatal and early postnatal period. The most known adverse factors causing developmental neurobehavioral dysfunctions in humans as well as in experimental animals are discussed.

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Ageing with cerebral palsy: psychosocial issues

Cited by 30 publications

References 17 publications

Leaders’ experiences and perceptions implementing activity-based funding and pay-for-performance hospital funding models: A systematic review

Leaders’ experiences and perceptions implementing activity-based funding and pay-for-performance hospital funding models: A systematic review

Prevalence of metabolic syndrome and cardiovascular disease risk factors in adults with cerebral palsy

Neurobehavioral manifestations of developmental impairment of the brain

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