Age-related hearing loss: Is it a preventable condition?

Bielefeld, Eric C.; Tanaka, Chiemi; Chen, Guangdi; Henderson, Donald

doi:10.1016/j.heares.2009.09.001

Cited by 90 publications

(93 citation statements)

References 105 publications

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“…Development of age-related hearing loss (ARHL) is determined by cumulative effects of individual's genetic predisposition and deleterious auditory exposures. While it may be difficult to modify genetic predisposition, it may be theoretically possible to prevent ARHL by minimizing ototraumatic exposures during the lifespan 10 . Environmental risk factors like exposure to noise, use of ototoxic drugs, head injuries are all modifiable.…”

Section: Discussionmentioning

confidence: 99%

Clinical and audiometric features of presbycusis in Nigerians

Sogebi¹,

Olusoga-Peters²,

Oluwapelumi³

2014

Afr H. Sci.

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Background: Presbycusis is the most common sensory impairment associated with ageing and it presents with variability of symptoms. Physicians need to recognize early clinical and audiometric signs of presbycusis in order to render adequate and quality care to patients and reduce associated morbidities. Objective: To characterize the clinical modes of presentation and the typical audiometric tracings among patients with presbycusis. Methods: This descriptive, prospective hospital-based study was conducted in the Ear, Nose and Throat (ENT) clinic of Olabisi Onabanjo University Teaching Hospital, (OOUTH) Sagamu, Nigeria. Patients with clinical diagnosis of presbycusis confirmed with bilateral sensorineural hearing loss (SNHL) on diagnostic audiometry were administered with questionnaires. Information obtained was analyzed using SPSS statistical package version 17.0 and presented in descriptive forms as percentages, means and graphs. Results: Sixty-nine patients were diagnosed with presbycusis (M:F =1.6:1). Modal age group was 71-80 years. Hearing loss 88.4%, tinnitus 79.7% and vertigo 33.3% were the major symptoms on presentation. The average duration of symptoms before presentation was 2.6 years. There was positive history of ototoxic drugs usage in 24.6 %, family history in 11.6 %, hypertension in 34.8% and osteoarthritis in 13.0%. The most common type of audiometric pattern was strial. Hearing losses increased with age both at the speech and at the higher frequencies of sounds. Conclusions: We found hearing impairment affected both speech and higher frequencies and the strial type of audiometric pattern was most common. The need for screening for hearing impairment from early middle age in symptomatic individuals is emphasized.

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Section: Discussionmentioning

confidence: 99%

Clinical and audiometric features of presbycusis in Nigerians

Sogebi¹,

Olusoga-Peters²,

Oluwapelumi³

2014

Afr H. Sci.

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“…"Pure tone averages" (PTA) were derived by calculating hearing loss at each frequency, averaged across the left and right ears. Given that age-related hearing loss begins at higher frequencies and, with increasing age, expands in both magnitude and extent, we separately explored the effects of hearing loss at these three frequencies (Bielefeld, Tanaka, Chen, & Henderson, 2010). To approximate verbal IQ, predicted verbal IQ was derived from the National Adult Reading Test (NART) (Nelson, 1982).…”

Section: Background Assessmentsmentioning

confidence: 99%

Is Age-related Decline in Vocal Emotion Identification an Artefact of Labelling Cognitions?

Mitchell

Kingston²

2011

IJPS

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Evidence has emerged that older adults find it more difficult to interpret prosodic emotions than younger adults. However, typical tasks involve labelling-related cognitions over and above emotion perception per se. Accordingly, we aimed to determine if age-related difficulty in prosodic emotion labelling extended to discrimination, which is more closely related to emotion perception per se. For this purpose, 45 younger adults (mean age 20 years, 2 males/43 females) and 45 older adults (mean age 71 years, 16 males/29 females) were recruited. In one task, participants heard pairs of sentences and were asked to indicate whether they were spoken with the same emotional intonational or not. In a second task, they heard sentences with intonation conveying a question or statement, and indicated whether the non-emotional intonation patterns matched or not. Older adults' performance consistently fell below that of younger adults. Older adults may have a generic prosodic decoding deficit, regardless of the end function of the prosody.

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“…In experimental models, hearing levels were evaluated in antioxidant therapy given as combination in hearing loss emerging with age, and improvement in hearing levels was proven with the BERA test [29]. In tests performed on humans following experimental studies, age-related hearing loss was shown to be prevented with diet and antioxidants [30]. In our study, PON1 and ARE values were found to be lower in metabolic presbycusis patients, compared to the control group.…”

Section: Discussionmentioning

confidence: 65%

The Relationship Between Metabolic Presbycusis and Serum Paraoxonase/Arylesterase Activity

Keleş

Kapusuz

Gürsu

et al. 2011

Indian J Otolaryngol Head Neck Surg

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To determine the presence of a relationship between metabolic presbycusis and serum paraoxonase/ arylesterase activity. A total of 30 patients who had been admitted to the Ear, Nose, and Throat (ENT) Clinic of Fırat University Medical Faculty and diagnosed as metabolic presbycusis were included in the study. The control group was composed of 30 healthy volunteers. Pure tone audiometry and impedencemeter were performed on all subjects included in the study at the audiometry laboratory of the ENT clinic. The presence of a regular hearing curve, a symmetrical sensorineural hearing loss more than 25 dB with preserved speech discrimination were accepted as criteria for metabolic presbycusis. Blood samples were drawn from the patients prior to the hearing tests. The sera were separated for measurements of total cholesterol, triglyceride, high-density lipoprotein, very low-density lipoprotein, low-density lipoprotein, human serum paraoxonase and arylesterase levels, respectively. No statistically significant difference was found between the patient and the control groups in terms of age and gender. Paraoxonase, arylesterase and paraoxonase/arylesterase, high-density lipoprotein levels were found to decrease in the study group and the difference was found to be statistically significant compared to the control group (P \ 0.001). Low-density lipoprotein and total cholesterol levels were found to increase in the patient group and the difference was found to be significant compared to the control group (P \ 0.001). This study puts forth that especially the type of nutrition and life style are very important with regard to metabolic presbycusis. Furthermore, the results of this study make us think that there could be a relationship between metabolic presbycusis and cardiovascular diseases. In this case, metabolic presbycusis may be a determining parameter in the early diagnosis of cardiovascular diseases. We consider that this study may be the pioneer for further studies conducted with larger patient numbers.

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Age-related hearing loss: Is it a preventable condition?

Cited by 90 publications

References 105 publications

Clinical and audiometric features of presbycusis in Nigerians

Clinical and audiometric features of presbycusis in Nigerians

Is Age-related Decline in Vocal Emotion Identification an Artefact of Labelling Cognitions?

The Relationship Between Metabolic Presbycusis and Serum Paraoxonase/Arylesterase Activity

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