Age-related effects of three inhalational anesthetics at one minimum alveolar concentration on electroencephalogram waveform

Tsukamoto, Masanori; Taura, Shiori; Yamanaka, Hitoshi; Hitosugi, Takashi; Kawakubo, Yoshifumi; Yokoyama, Takeshi

doi:10.1007/s40520-019-01378-1

Cited by 7 publications

(18 citation statements)

References 30 publications

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“…With regard to age being a factor, two demonstrated that elderly patients appeared to have higher SEF values than adult patients ≤67 years of age for 1 MAC desflurane or sevoflurane. 16 , 17 These findings suggest that that older patients do not require as low SEF values as younger patients. 16 , 17 A similar result was observed by a study of propofol administered using target-controlled infusion.…”

Section: Discussionmentioning

confidence: 85%

“… 16 Younger participants generally had lower SEF values regardless of whether desflurane or sevoflurane was administered ( Table 3) . 16 From the results obtained by the other study, 17 the value of SEF for desflurane and isoflurane appeared to have been higher in elderly patients (69.5–83.5 years) than in younger adult and middle-aged patients (26.9–53.9 years). However, the SEF value was higher in the group of elderly patients when sevoflurane was administered.…”

Section: Sef and Different Anaesthetic Agentsmentioning

confidence: 82%

“…However, the SEF value was higher in the group of elderly patients when sevoflurane was administered. 17 This result emerged at a lower frequency for 1 MAC desflurane than for 1 MAC sevoflurane or isoflurane. 17 SEF values increased with patient age (40–90 years) for all inhalational anaesthetic agents.…”

Section: Sef and Different Anaesthetic Agentsmentioning

confidence: 91%

“… 17 SEF values increased with patient age (40–90 years) for all inhalational anaesthetic agents. 17 The previous showed that if the value of MAC was kept at 1 for sevoflurane and desflurane, no burst suppression or epileptiform discharge occurred. 16 …”

Section: Sef and Different Anaesthetic Agentsmentioning

confidence: 96%

“…Two RCTs aimed to investigate SEF in various age groups when inhalational anaesthetic agents were administered at 1 minimum alveolar concentration (MAC). 16 , 17 One study compared the value of SEF among young, middle-aged and elderly patients. 16 The results showed that 1 MAC desflurane affords a lower SEF value than 1 MAC sevoflurane (12.53 Hz versus 14.42 Hz).…”

Section: Sef and Different Anaesthetic Agentsmentioning

confidence: 99%

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Spectral edge frequency during general anaesthesia: A narrative literature review

et al. 2022

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Previous studies have attempted to determine the depth of anaesthesia with different anaesthetic agents using electroencephalogram (EEG) measurements with variable success. Measuring depth of anaesthesia is confounded by the complexity of the EEG and the fact that different agents create different pattens. A narrative review was undertaken to examine the available research evidence on the effect and reliability of spectral edge frequency (SEF) for assessing the depth of anaesthesia in adult patients under general anaesthesia. A systematic search of the PubMed®, Scopus®, CINAHL and Cochrane databases identified six randomized controlled trials and five observational studies. The findings of these studies suggest that SEF varies according to the anaesthetic drugs used. Remifentanil and age are two factors that can affect SEF, while other opioids and benzodiazepine (administered separately) seem to have no effect. No patients experienced intraoperative awareness. However, this does not indicate that SEF can provide full protection against it and the number of articles in which intraoperative awareness was studied was too small to afford any certainty. None of the studies demonstrated a reliable SEF interval associated with adequate general anaesthesia. SEF must be adapted to the anaesthetic drug used, the patient’s age and state while under general anaesthesia.

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Section: Discussionmentioning

confidence: 85%

Section: Sef and Different Anaesthetic Agentsmentioning

confidence: 82%

Section: Sef and Different Anaesthetic Agentsmentioning

confidence: 91%

Section: Sef and Different Anaesthetic Agentsmentioning

confidence: 96%

Section: Sef and Different Anaesthetic Agentsmentioning

confidence: 99%

See 3 more Smart Citations

Spectral edge frequency during general anaesthesia: A narrative literature review

et al. 2022

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The influence of age on EEG-based anaesthesia indices

Obert

Schweizer

Zinn

et al. 2021

Journal of Clinical Anesthesia

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Comparison of the tidal volume by the recruitment maneuver combined with positive end-expiratory pressure for mechanically ventilated children

Tsukamoto,

Goto,

Hitosugi

et al. 2023

Sci Rep

Self Cite

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The recruitment maneuver (RM) combined with PEEP to prevent atelectasis have beneficial effects. However, the change in tidal volume (VT) due to RM combined with PEEP in pediatric patients during the induction of general anesthesia is unknown. Therefore, we assessed the effects of RM combined with PEEP on VT. Pediatric patients were divided into three groups: infants, preschool children, and school children. The RM was performed by maintaining pressure control continuous mandatory ventilation (PC-CMV) with a 15 cmH2O and PEEP increase of 5 cmH2O. VT, respiratory function and hemodynamics were monitored before and after RM combined with PEEP. VT (mL) /ideal body weight (kg) before vs. after RM combined with PEEP were 9 vs 12 mL/kg (p < 0.05) in the infants, 9 vs 11 mL/kg (p < 0.05) in the preschool children, 8 vs 10 mL/kg (p < 0.05) in the school children, respectively. HR and BP before and after RM combined with PEEP increased by 2–3% and decreased by 4–7% in all groups. RM combined with PEEP resulted in an increase in VT per ideal body weight (1.1–1.2%). Therefore, this RM combined with PEEP method might improve the lung function in pediatric patients.

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Age-related effects of three inhalational anesthetics at one minimum alveolar concentration on electroencephalogram waveform

Cited by 7 publications

References 30 publications

Spectral edge frequency during general anaesthesia: A narrative literature review

Spectral edge frequency during general anaesthesia: A narrative literature review

The influence of age on EEG-based anaesthesia indices

Comparison of the tidal volume by the recruitment maneuver combined with positive end-expiratory pressure for mechanically ventilated children

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