volume 93, issue 0, P2-P-203 2020
DOI: 10.1254/jpssuppl.93.0_2-p-203
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Suo Zou,
Takahiro Shimizu,
Shogo Shimizu
et al.

Abstract: We have confirmed that hydrogen sulfide (H 2 S) is a possible relaxation factor in the rat bladder, and H 2 S-induced bladder relaxation is impaired in 18-week-old (18W) spontaneously hypertensive rats (SHRs), which show bladder dysfunctions. We compared effects of NaHS and GYY4137 (H 2 S donors) on bladder contractility and micturition reflex, and H 2 S contents and expression of enzymes related to H 2 S biosynthesis (CBS, MPST and CAT) in the bladder between 12W and 18W male SHRs. Effects of NaHS (1×10-8 to …

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