Age-related differences in glycaemic control, cardiovascular disease risk factors and treatment in patients with type 2 diabetes: a cross-sectional study from the Australian National Diabetes Audit

Nanayakkara, Natalie; Ranasinha, Sanjeeva; Gadowski, Adelle; Davis, Wendy A.; Flack, J.; Wischer, Natalie; Andrikopoulos, Sof; Zoungas, Sophia

doi:10.1136/bmjopen-2017-020677

Cited by 26 publications

(32 citation statements)

References 32 publications

(33 reference statements)

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“…In stratified analysis, we reanalyzed the data for gender and age groups, and we showed that DM only in females and patients younger than 65 years increased the risk of death. Previous observations confirmed the age and gender differences in glycemic control and treatment responses in diabetic patients [26][27][28][29][30]. According to the evidence, women with DM are less likely to reach the ideal level of hemoglobin A1c (HbA1c) compared with men [26,27,30].…”

Section: Table 4 Predicting Factors For Death Of the Covid-19 In Patimentioning

confidence: 68%

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Risk and predictors of in-hospital mortality from COVID-19 in patients with diabetes and cardiovascular disease

Rastad

Karim

Ejtahed

et al. 2020

Diabetol Metab Syndr

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Background: Diabetes mellitus (DM) and cardiovascular disease (CVD) are present in a large number of patients with novel Coronavirus disease 2019 (COVID-19). We aimed to determine the risk and predictors of in-hospital mortality from COVID-19 in patients with DM and CVD. Methods: This retrospective cohort study included hospitalized patients aged ≥ 18 years with confirmed COVID-19 in Alborz province, Iran, from 20 February 2020 to 25 March 2020. Data on demographic, clinical and outcome (in-hospital mortality) data were obtained from electronic medical records. Self-reported comorbidities were classified into the following groups: "DM" (having DM with or without other comorbidities), "only DM" (having DM without other comorbidities), "CVD" (having CVD with or without other comorbidities), "only CVD" (having CVD without other comorbidities), and "having any comorbidity". Multivariate logistic regression models were fitted to quantify the risk and predictors of in-hospital mortality from COVID-19 in patients with these comorbidities. Results: Among 2957 patients with COVID-19, 2656 were discharged as cured, and 301 died. In multivariate model, DM (OR: 1.62 (95% CI 1.14-2.30)) and only DM (1.69 (1.05-2.74)) increased the risk of death from COVID-19; but, both CVD and only CVD showed non-significant associations (p > 0.05). Moreover, "having any comorbidities" increased the risk of in-hospital mortality from COVID-19 (OR: 2.66 (95% CI 2.09-3.40)). Significant predictors of mortality from COVID-19 in patients with DM were lymphocyte count, creatinine and C-reactive protein (CRP) level (all P-values < 0.05). Conclusions: Our findings suggest that diabetic patients have an increased risk of in-hospital mortality following COVID-19; also, lymphocyte count, creatinine and CRP concentrations could be considered as significant predictors for the death of COVID-19 in these patients.

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Section: Table 4 Predicting Factors For Death Of the Covid-19 In Patimentioning

confidence: 68%

“…The risk of all-cause mortality was higher in females with DM. Moreover, surveys showed that younger adults have poorer glycemic control compared to older diabetic patients [28,29]. These issues are of great importance in interpreting the findings of epidemiological studies.…”

Section: Table 4 Predicting Factors For Death Of the Covid-19 In Patimentioning

confidence: 99%

Risk and predictors of in-hospital mortality from COVID-19 in patients with diabetes and cardiovascular disease

Rastad

Karim

Ejtahed

et al. 2020

Diabetol Metab Syndr

View full text Add to dashboard Cite

show abstract

“…In strati ed analysis, we reanalyzed the data for gender and age groups, and we showed that DM only in females and patients younger than 65 years increased the risk of death. Previous observations con rmed the age and gender differences in glycemic control and treatment responses in diabetic patients [26][27][28][29][30]. According to the evidence, women with DM are less likely to reach the ideal level of hemoglobin A1c (HbA1c) compared with men [26,27,30].…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Risk and predictors of in-hospital mortality from COVID-19 in patients with diabetes and cardiovascular disease

Rastad

Karim

Ejtahed

et al. 2020

Preprint

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Background: Diabetes mellitus (DM) and cardiovascular disease (CVD) are present in a large number of patients with novel Coronavirus disease 2019 (COVID-19). We aimed to determine the risk and predictors of in-hospital mortality from COVID-19 in patients with DM and CVD.Methods: This retrospective cohort study included hospitalized patients aged ≥ 18 years with confirmed COVID-19 in Alborz province, Iran, from 20 February 2020 to 25 March 2020. Data on demographic, clinical and outcome (in-hospital mortality) data were obtained from electronic medical records. Self-reported comorbidities were classified into the following groups: “DM” (having DM with or without other comorbidities), “only DM” (having DM without other comorbidities), “CVD” (having CVD with or without other comorbidities), “only CVD” (having CVD without other comorbidities), and “having any comorbidity”. Multivariate logistic regression models were fitted to quantify the risk and predictors of in-hospital mortality from COVID-19 in patients with these comorbidities.Results: Among 2957 patients with COVID-19, 2656 were discharged as cured, and 301 died. In multivariate model, DM (OR: 1.62 (95%CI: 1.14-2.30)) and only DM (1.69 (1.05-2.74)) increased the risk of death from COVID-19; but, both CVD and only CVD showed non-significant associations (p>0.05). Moreover, “having any comorbidities” increased the risk of in-hospital mortality from COVID-19 (OR: 2.66 (95%CI: 2.09 -3.40)). Significant predictors of mortality from COVID-19 in patients with DM were lymphocyte count, creatinine and C-reactive protein (CRP) level (all P- values < 0.05).Conclusions: Our findings suggest that diabetic patients have an increased risk of in-hospital mortality following COVID-19; also, lymphocyte count, creatinine and CRP concentrations could be considered as significant predictors for the death of COVID-19 in these patients.

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“…Los años de diagnóstico influyeron de forma inversa en el autocuidado. Esto difiere con otro estudio 55 , en el que el bajo control glucémico en personas se asocia con quienes tienen menos de seis años con la enfermedad. Lo anterior indica que la evolución de la diabetes es una condición que puede limitar el autocuidado y asociarse al descontrol glucémico.…”

Section: Discussionunclassified

Hombres con diabetes mellitus tipo 2: autoeficacia y factores psicológicos que influyen en el autocuidado

et al. 2020

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Introducción: La prevalencia global de diabetes mellitus tipo 2 (DMT2) en los hombres es alta. Para el tratamiento de la enfermedad el hombre debe realizar acciones de autocuidado, por lo que es importante conocer factores relacionados con su cumplimiento. Objetivo: Identificar la relación entre variables demográficas, clínicas, la angustia, la depresión, la autoeficacia y su influencia sobre el autocuidado en hombres con DMT2. Métodos: Estudio transversal y correlacional, en una muestra de 96 hombres con DMT2, usuarios de 13 centros de salud. Los instrumentos utilizados fueron el cuestionario de acciones de cuidado en diabetes, la escala Self-Efficacy for Diabetes, la escala depresión (CES-D) y la escala angustia por diabetes (DDS). Resultados: El autocuidado se correlacionó de manera positiva con la autoeficacia y negativamente con la angustia por diabetes. Las variables que explicaron el autocuidado con el 47.7% de varianza fueron: la autoeficacia (β = .39), el consumo de alcohol (β = -.29), las horas sentado/parado (β= -.27), el tiempo de diagnóstico (β= -.22) y la edad (β =.18). Discusión: Los hombres tuvieron un bajo autocuidado y mantienen conductas de riesgo, lo cual puede atribuirse a sus creencias, estilo de vida o al tipo de trabajo que desempeñan. Conclusiones: Los resultados ofrecen evidencia sobre factores que influyen en el autocuidado de hombres con DMT2, que pueden orientar a los profesionales de enfermería en la atención del paciente. Se sugiere realizar investigaciones de enfermería en hombres, que contribuyan a mejorar la autoeficacia y el autocuidado.

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Age-related differences in glycaemic control, cardiovascular disease risk factors and treatment in patients with type 2 diabetes: a cross-sectional study from the Australian National Diabetes Audit

Cited by 26 publications

References 32 publications

Risk and predictors of in-hospital mortality from COVID-19 in patients with diabetes and cardiovascular disease

Risk and predictors of in-hospital mortality from COVID-19 in patients with diabetes and cardiovascular disease

Risk and predictors of in-hospital mortality from COVID-19 in patients with diabetes and cardiovascular disease

Hombres con diabetes mellitus tipo 2: autoeficacia y factores psicológicos que influyen en el autocuidado

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