Age-related changes of the dental pulp complex and their relationship to systemic aging

Morse, Donald R.

doi:10.1016/0030-4220(91)90019-9

Cited by 167 publications

(134 citation statements)

References 24 publications

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“…In a dynamic interplay of cell proliferation and cell death, the developing tooth retains precisely the type and number of cells needed to proceed into maturity. It is admitted that odontoblasts are terminally differentiated cells that survive as long as the integrity of the tooth is preserved [12,13]. However, the dental pulp volume decreases gradually on ageing due to the continuous production of dentin matrix by odontoblasts.…”

Section: Introductionmentioning

confidence: 99%

“…First, as odontoblasts must survive for the entire life span of the animal in spite of the continuous decrease of the dental pulp chamber volume [12,13], an understanding of the regulatory mechanisms that control cell death in dental pulp may provide new insights into the process of tooth homeostasis. Second, conditions or agents that initiate apoptosis (i.e.…”

Section: Introductionmentioning

confidence: 99%

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Apoptosis in developmental and repair-related human tooth remodeling: A view from the inside

Mitsiadis

Bari

About

2008

Experimental Cell Research

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Apoptosis in developmental and repair-related human tooth remodeling: A view from the inside

Mitsiadis

Bari

About

2008

Experimental Cell Research

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“…Así, se identificó un aumento en la presencia de fibras de colágeno en la región central de la pulpa en los ratones de 12 semanas al compararlos con los de 4 semanas. Estos hallazgos son congruentes con los reportados por 15,30,60,90, 125 y 400 días de edad y con la asociación al proceso de envejecimiento pulpar (Schofield & Weightman;Morse, 1991).…”

Section: Discussionunclassified

Características Histológicas de la Pulpa Dental de Ratones de 4 y 12 Semanas

Salazar

Monsalve

2014

Int. J. Odontostomat.

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RESUMEN:En condiciones fisiológicas, el órgano dentinopulpar no se encuentra asociado a procesos de remodelación y resorción. Los hallazgos histológicos muestran que la pulpa presenta características especiales como tejido conectivo que le confieren su capacidad de adaptación. El propósito del presente estudio fue evaluar las características histológicas de la pulpa dental de ratones de la cepa Albino Suizo de 4 y 12 semanas de edad. Ocho hemimandíbulas de ratones albino suizo de 4 y 12 semanas de edad fueron utilizados. Las hemimandíbulas fueron fijadas en Paraformaldehído al 4%, sometidas a decalcificación con EDTA al 5% durante 10 días a 4ºC e incluidas en Paraplast®. Se obtuvieron secciones de 5 µm que fueron teñidos con H&E, Tricrómico de Masson e Impregnación Argéntica. Las características histológicas de la pulpa revelaron dos zonas principales en ambos grupos de edad: la zona periférica pulpar conformada por un conjunto de células compatibles con odontoblastos y una zona pobre en células, y otra zona central pulpar, rica en fibroblastos y vasos sanguí-neos. Las diferencias entre los grupos de edad se vieron en la expresión de matriz fibrilar de colágeno. Se encontraron semejanzas en la presencia de fibras reticulares entre los grupos. La pulpa dentaria en ratones Albino Suizo mostró una división en dos zonas: central y periférica, con grupos poblacionales bien definidos. La mayor diferencia por edad estuvo en la cantidad de colágeno.

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“…The circulation and innervations can rapidly become compromised, reparative dentin can be laid down at accelerated pace, and fibrosis and calcification can occur [27]. Protective pulpal response to irritation, such as secondary dentin formation, results in a decrease in the size of pulp chamber, and degenerative diffuse calcification might result in reduced ability to detect pulp stones in these teeth during radiographic examination [8].…”

Section: Association With Systemic Conditionsmentioning

confidence: 99%

Hard Facts about Stones: Pulpal Calcifications: A Review

Vibhute¹

2017

J Pat Care

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Pulp calcifications stones are discrete calcifications within the pulps of teeth. They are a frequent finding on bitewing and periapical radiographs. Johnson and Bevelander stated that a single tooth may have stones ranging from 1 to 12 or even more, with sizes varying from minute particle to large masses that occlude the pulp space. They often develop in teeth that appear quite normal in other respects. They have been seen in both functional as well as embedded teeth. Inspite of this frequent occurrence, they have received relatively little attention in textbooks. The purpose of this review was to examine these pulp stones from all the aspects including their pathogenesis, clinical aspects, histopathology, current perspectives and contemporary research on the same.

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Age-related changes of the dental pulp complex and their relationship to systemic aging

Cited by 167 publications

References 24 publications

Apoptosis in developmental and repair-related human tooth remodeling: A view from the inside

Apoptosis in developmental and repair-related human tooth remodeling: A view from the inside

Características Histológicas de la Pulpa Dental de Ratones de 4 y 12 Semanas

Hard Facts about Stones: Pulpal Calcifications: A Review

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