Age-related changes in intraoperative mean values of nociceptive response in patients undergoing non-cardiac surgery under general anesthesia: A retrospective cohort study

When nociception monitoring becomes predictive of surgical outcomes : has the future already become real ?

“…In the present edition of the Journal of Clinical Monitoring and Computing, Miyamoto et al present the retrospective analysis of NR index on a massive dataset of 22,061 patients, with subgroup analysis concerning age groups and surgical risk [ 16 ]. This retrospective study is one of several undertaken by the authors in order to assess the clinical utility, potential bias and predictive thresholds of the NR index.…”