Age-related behavior of posterior chamber lenses in myopic phakic eyes during accommodation measured by anterior segment partial coherence interferometry

Abstract

The behavior of ICLs in relation to the crystalline lens during accommodation varied with age and could be shown by PCI. The position shift of the ICL depended on the initial vault at desaccommodation and the ability of the anterior lens surface to bulge forward. Even though the crystalline lens stiffened, and therefore accommodation deteriorated with age, there was still a movement of the ICL, pointing to the role of the ciliary muscle movement in accommodation.

Central vault after phakic intraocular lens implantation: Correlation with anterior chamber depth, white-to-white distance, spherical equivalent, and patient age

“…The hyperopic pIOLs had the lowest mean values and the toric pIOLs the highest mean values. This agrees with previous findings 18,19 and is the result of the inherent design of each pIOL type and of the different anatomy of hyperopic, myopic, and astigmatic eyes. The myopic pIOL is plano concave, with the plano surface facing anteriorly, and it has an optic diameter ranging from 4.65 to 5.50 mm.…”

“…Thus, factors such as accommodation and biometric ocular changes related to aging affect the space available between the posterior cornea and anterior crystalline lens surface, which in turn affects the amount of vault. 14,19,[26][27][28][29][30] Thus, achieving satisfactory vault is important for safe and successful pIOL implantation. In the U.S. Food and Drug Administration Implantable Collamer Lens study, 31 which implemented the WTW measurement protocol, the pIOL replacement rate because of clinically significant oversizing or undersizing was 1.5%.…”

Anterior segment changes with age and during accommodation measured with partial coherence interferometry

“…[22][23][24] Our data correlate well with these facts. It is also known that the age-dependent thickening of the lens is mainly caused by the increase in the anterior and posterior cortical layers.…”

Three-year follow-up of subjective vault following myopic implantable collamer lens implantation

“…They also reported a significant reduction (−73±50 µm) in vault under photopic conditions, which is supposed to reflect the effect of pupil miosis on ICL position. Lege et al [26] reported a significant relationship between age and vault variation during accommodation, with vault showing a trend to decrease in younger patients and to increase in older individuals, which may be a consequence of the higher accommodative activity in young subjects. However, beyond the influence of these physiological factors on the separation of ICL and the lens, it is possible that the vault will change over time after surgery, probably decreasing in a number of cases, which is a significant concern with regard to the risk of lens opacity.…”