Age of menarche is associated with knee joint replacement due to primary osteoarthritis (The HUNT Study and the Norwegian Arthroplasty Register)

Abstract

We found that increasing age at menarche reduced the risk of TKR. Past users and users of systemic HRT were at higher risk of TKR compared to never users. Parity did not increase the risk of THR or TKR.

Ultrasound assessment of pubertal breast development in girls: intra- and interobserver agreement

“…However, larger population-based studies following similar designs and conducted in different geographical areas within Norway should be carried out to explore how the trend of pubertal timing develops in Norway. (58,65,66,78,(187)(188)(189)(190)(191)(192)(193)(194). Open markers are retrospective surveys in adult women.…”

An Analysis of Early Outcomes of Knee Osteoarthritis Surgical Treatment

“…Частота инвалидизации достигает 20 %, а снижение качества жизни, связанное с данной патологией, отмечают у 80 % пациентов. Встречаемость заболевания повышается с возрастом и развивается после 35-50 лет в 30-40 %, а после 65 лет в 60-70 % случаев, при этом соотношение заболеваемости мужчин и женщин -1:3 [2,3]. В этой связи основной целью данной работы является анализ ближайших результатов оперативного лечения, а также выявление взаимосвязи предрасполагающих факторов и развития заболевания.…”

Female Reproductive and Hormonal Factors and Incidence of Primary Total Knee Arthroplasty Due to Osteoarthritis

“…A number of studies have examined the association of reproductive and hormonal factors with knee OA, but the results are inconclusive. Increasing parity has been reported as a risk factor for radiographic knee OA and total knee arthroplasty (TKA) for OA , while other studies have found no association of parity with radiographic knee OA or TKA due to OA . A large prospective cohort study found increased risk of TKA associated with low age at menarche , but this finding was contradicted by another large‐scale cohort study showing no association .…”

“…Increasing parity has been reported as a risk factor for radiographic knee OA and total knee arthroplasty (TKA) for OA , while other studies have found no association of parity with radiographic knee OA or TKA due to OA . A large prospective cohort study found increased risk of TKA associated with low age at menarche , but this finding was contradicted by another large‐scale cohort study showing no association . No associations have been reported of the use of oral contraceptives (OCs) with knee cartilage volume , radiographic knee OA , or TKA .…”

“…A large prospective cohort study found increased risk of TKA associated with low age at menarche , but this finding was contradicted by another large‐scale cohort study showing no association . No associations have been reported of the use of oral contraceptives (OCs) with knee cartilage volume , radiographic knee OA , or TKA . While hormone replacement therapy (HRT) has been shown to be a protective factor for knee cartilage and to protect against radiographic knee OA , other studies have found no association of HRT with knee pain due to OA , with knee cartilage , or with TKA .…”