Age mediation of frontoparietal activation during visual feature search

Madden, David J.; Parks, EL; Davis, Simon W.; Diaz, Michèle T.; Potter, Guy G.; Chou, Ying-hui; Chen, Nan‐kuei; Cabeza, Roberto

doi:10.1016/j.neuroimage.2014.07.053

Cited by 25 publications

(34 citation statements)

References 90 publications

(172 reference statements)

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“…Proulx [] proposed that participants were adopting a search strategy in which they were relying on bottom‐up guidance from the size singleton to prioritize display items for further processing. In our recent study of visual feature search, the left FEF was one among three prefrontal regions with a significant activation‐RT correlation when a salient distractor was present [Madden et al, ]. Several forms of evidence, including the effects of intracortical microstimulation [Moore and Armstrong, ], neurotransmitter modulation [Noudoost and Moore, ], and cortical lesions [Rossi et al, ], suggest that FEF is a specific site of top‐down signals enhancing the activity within visual cortical regions [Miller and Buschman, ; Noudoost et al, ].…”

Section: Discussionmentioning

confidence: 99%

Frontoparietal activation during visual conjunction search: Effects of bottom‐up guidance and adult age

Madden

Parks

Tallman

et al. 2017

Human Brain Mapping

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We conducted functional magnetic resonance imaging (fMRI) with a visual search paradigm to test the hypothesis that aging is associated with increased frontoparietal involvement in both target detection and bottom-up attentional guidance (featural salience). Participants were 68 healthy adults, distributed continuously across 19-78 years of age. Frontoparietal regions of interest (ROIs) were defined from resting-state scans obtained prior to task-related fMRI. The search target was defined by a conjunction of color and orientation. Each display contained one item that was larger than the others (i.e., a size singleton) but was not informative regarding target identity. Analyses of search reaction time (RT) indicated that bottom-up attentional guidance from the size singleton (when coincident with the target) was relatively constant as a function of age. Frontoparietal fMRI activation related to target detection was constant as a function of age, as was the reduction in activation associated with salient targets. However, for individuals 35 years of age and older, engagement of the left frontal eye field (FEF) in bottom-up guidance was more prominent than for younger individuals. Further, the age-related differences in left FEF activation were a consequence of decreasing resting-state functional connectivity in visual sensory regions. These findings indicate that age-related compensatory effects may be expressed in the relation between activation and behavior, rather than in the magnitude of activation, and that relevant changes in the activation-RT relation may begin at a relatively early point in adulthood.

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Section: Discussionmentioning

confidence: 99%

Frontoparietal activation during visual conjunction search: Effects of bottom‐up guidance and adult age

Madden

Parks

Tallman

et al. 2017

Human Brain Mapping

Self Cite

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“…Also, older adults are less effective at avoiding being distracted by external salient stimuli (Madden et al, 2014). Yet voluntary attention shifting, or top-down attention, shows little influence of age (Greenwood et al, 1993, Madden, 2007).…”

Section: Relations Between Emotional Processing In Aging and Brain Fumentioning

confidence: 99%

The Affective Neuroscience of Aging

Mather

2016

Annu. Rev. Psychol.

218

215

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While aging is associated with clear declines in physical and cognitive processes, emotional functioning fares relatively well. Consistent with this behavioral profile, two core emotional brain regions, the amygdala and ventromedial prefrontal cortex, show little structural and functional decline in aging, compared with other regions. However, emotional processes depend on interacting systems of neurotransmitters and brain regions that go beyond these structures. This review examines how age-related brain changes influence processes such as attending to and remembering emotional stimuli, regulating emotion, recognizing emotional expressions, empathy, risk taking, impulsivity, behavior change and attentional focus.

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“…Moreover, these frontoparietal regions play a role in biasing processing toward the top-down defined information and in preventing salient distractors from interfering with target search (Chun & Marois, 2002;Friedman-Hill et al, 2003;Madden et al, 2014;Marois, Chun, & Gore, 2000). Moreover, these frontoparietal regions play a role in biasing processing toward the top-down defined information and in preventing salient distractors from interfering with target search (Chun & Marois, 2002;Friedman-Hill et al, 2003;Madden et al, 2014;Marois, Chun, & Gore, 2000).…”

Section: Processing the Task-relevant Dimensionmentioning

confidence: 99%

Differential brain mechanisms for processing distracting information in task‐relevant and ‐irrelevant dimensions in visual search

Wei

Müller³

et al. 2018

Human Brain Mapping

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A crucial function of our goal-directed behavior is to select task-relevant targets among distractor stimuli, some of which may share properties with the target and thus compete for attentional selection. Here, by applying functional magnetic resonance imaging (fMRI) to a visual search task in which a target was embedded in an array of distractors that were homogeneous or heterogeneous along the task-relevant (orientation or form) and/or task-irrelevant (color) dimensions, we demonstrate that for both (orientation) feature search and (form) conjunction search, the fusiform gyrus is involved in processing the task-irrelevant color information, while the bilateral frontal eye fields (FEF), the cortex along the left intraparietal sulcus (IPS), and the left junction of intraparietal and transverse occipital sulci (IPTO) are involved in processing task-relevant distracting information, especially for target-absent trials. Moreover, in conjunction (but not in feature) search, activity in these frontoparietal regions is affected by stimulus heterogeneity along the task-irrelevant dimension: heterogeneity of the task-irrelevant information increases the activity in these regions only when the task-relevant information is homogeneous, not when it is heterogeneous. These findings suggest that differential neural mechanisms are involved in processing task-relevant and task-irrelevant dimensions of the searched-for objects. In addition, they show that the top-down task set plays a dominant role in determining whether or not task-irrelevant information can affect the processing of the task-relevant dimension in the frontoparietal regions.

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Age mediation of frontoparietal activation during visual feature search

Cited by 25 publications

References 90 publications

Frontoparietal activation during visual conjunction search: Effects of bottom‐up guidance and adult age

Frontoparietal activation during visual conjunction search: Effects of bottom‐up guidance and adult age

The Affective Neuroscience of Aging

Differential brain mechanisms for processing distracting information in task‐relevant and ‐irrelevant dimensions in visual search

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