Age, gender, and voided volume dependency of peak urinary flow rate and uroflowmetry nomogram in the Indian population

Abstract

Objectives:The objective of this study was measurement of urine flow parameters by a non invasive urodynamic test. Variation of flow rates based on voided volume, age, and gender are described. Different nomograms are available for different populations and racial differences of urethral physiology are described. Currently, there has been no study from the Indian population on uroflow parameters. So the purpose of this study was to establish normal reference ranges of maximum and average flow rates, to see the influence of age, gender, and voided volume on flow rates, and to chart these values in the form of a nomogram.Methods:We evaluated 1,011 uroflowmetry tests in different age groups in a healthy population (healthy relatives of our patients) 16-50 year old males, >50 year old males, 5-15 year old children, and >15 year pre-menopausal and post-menopausal females. The uroflowmetry was done using the gravitimetric method. Flow chart parameters were analyzed and statistical calculations were used for drawing uroflow nomograms.Results:Qmax values in adult males were significantly higher than in the elderly and Qmax values in young females were significantly higher than in young males. Qmax values in males increased with age until 15 years old; followed by a slow decline until reaching 50 years old followed by a rapid decline after 50 years old even after correcting voided volume. Qmax values in females increased with age until they reached age 15 followed by decline in flow rate until a pre-menopausal age followed by no significant decline in post-menopausal females. Qmax values increased with voided volume until 700 cc followed by a plateau and decline.Conclusions:Qmax values more significantly correlated with age and voided volume than Qavg. Nomograms were drawn in centile form to provide normal reference ranges. Qmax values in our population were lower than described in literature. Patients with voided volume up to 50 ml could be evaluated with a nomogram.

Utility and cost-effectiveness of uroflowmetry in a busy pediatric urology practice

“…[9][10][11][12] There is also little evidence with regards to the usefulness and effectiveness of UF for different conditions in children. 13 UF has been used commonly in patients with VD and postoperative hypospadias and our data support these indications. Diagnosis of VD in children can be a challenge to pediatric urologists.…”

Rationalization of interpretation of uroflowmetry for a non‐caucasian (Indian) population: conceptual development and validation of volume‐normalized flow rate index

“…Nevertheless, the VQI seems to be a more universal concept since our final definition is quadratic one similar to that of Von Garrelts (Caucasian). Another limitation is not incorporating age which is another important determinant of flow rates. Kumar et al found a weak correlation between flow rates and age both below and beyond 50 years of age ( R 2 = 0.02, P = 0.012 and R 2 = 0.09, P = 0.001, respectively). In our study of men aged 18–50 years, the correlation between flow rates and age was weak ( R 2 = 0.019, P = 0.001 for cQ max and R 2 = 0.017, P = 0.002 for cQ ave ).…”

Critical Analysis of the Use of Uroflowmetry for Urethral Stricture Disease Surveillance

“…11,12 Younger patients demonstrate more robust flow due to stronger bladder contractions and less prostatic obstruction. In this study, both Q m and Q m -Q a demonstrated superior predictive capability in detecting stricture recurrence in patients ≤40 years of age (AUC of 0.9224 and 0.9324, respectively) compared to patients >40 years of age (AUC of 0.7661 and 0.7484, respectively).…”