Age-dependent rebound in asthma exacerbations after COVID-19 lockdown

Hazan, Guy; Fox, Carolyn; Mok, H.; Haspel, Jeffrey A.

doi:10.1016/j.jacig.2022.06.001

Cited by 4 publications

(1 citation statement)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…An atypical surge prior to the normal peak in December to February has been reported. 25 , 27 Similar to the overcorrection theory postulated by Hazan et al 28 , Bardsley et al 23 hypothesized that the lack of RSV during winter 2020 to 2021 led to an “immunity debt,” with young children who did not have previous immunity to RSV becoming more susceptible to infection when health precautions were relaxed.…”

Section: Discussionmentioning

confidence: 95%

Prolonged School Closure and Pediatric Respiratory Hospitalization: The Silver Lining of the COVID-19 Pandemic

Bazzi,

Sallman,

Greenwell

et al. 2024

Global Pediatric Health

View full text Add to dashboard Cite

Objective. This is a single-center retrospective cohort study that aimed to quantitatively assess the association between prolonged school closure (>2 weeks) and pediatric respiratory hospitalization during the COVID-19 pandemic. Methods. Subjects included 1243 patients presenting to Children’s Hospital of Michigan during the winters of 2019, 2020, and 2021. The primary outcome measures were total respiratory hospitalizations and respiratory diagnoses. Results. Data was analyzed using a 2-sample z-test for proportions. We found that pediatric patients in the setting of prolonged school closure had significantly fewer hospitalizations in 2020 compared to 2019 (9% vs 47%; P < .001) and 2021 (9% vs 45%; P < .001). There were decreases in bronchiolitis, asthma/reactive airway disease (RAD), and pneumonia hospitalizations compared to 2019 and 2021. Conclusions. Our study showed that during prolonged school closure, there was a significant decrease in pediatric respiratory hospitalization. As such, it should be considered when creating a pandemic response strategy.

show abstract