Age dependency of resistance to cerebrospinal fluid outflow

Albeck, Michael; Skak, C.; Nielsen, Per Peetz; Olsen, Karsten Skovgaard; Børgesen, S. E.; Gjerris, F.

doi:10.3171/jns.1998.89.2.0275

Cited by 112 publications

(60 citation statements)

References 19 publications

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“…In children with craniosynostosis aged 0-15 years, mean ICP increased with increasing age until 6 years of age, when ICP declined with increasing age [15]. In adults, evidence for a relationship between age and ICP has been given [20], though others have reported no significant relationship between ICP and age [21].…”

Section: Comparisons Of Icp In Patients Undergoing Surgery or Conservmentioning

confidence: 91%

“…A suitable width/threshold matrix was selected, specifying the width/threshold combinations. In this study, the software recorded the numbers of samples that fitted a given combination of width (0.5, 1, 5, 10 or 20 min) and thresholds (20,25,30,35 or 40 mm Hg). The output from the analysis was a matrix containing the numbers of the different with and threshold combinations.…”

Section: Quantitative Analysis Of Icpmentioning

confidence: 99%

See 1 more Smart Citation

Differences in Quantitative Characteristics of Intracranial Pressure in Hydrocephalic Children Treated Surgically or Conservatively

Eide¹,

Due-Tønnessen²,

Helseth³

et al. 2002

Pediatr Neurosurg

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This study reports the results of quantitative analysis of continuous intracranial pressure (ICP) recordings in 33 hydrocephalic children. The aim of the study was to compare the exact numbers of increases in ICP during sleep or the awake state in hydrocephalic children who were treated either surgically or conservatively. At the time of ICP monitoring, the ICP curves were assessed by the calculation of mean ICP and visual inspection for the detection of plateau waves. Quantitative analysis was performed with the software Sensometrics^TM Pressure Analyser, which presented the ICP curve as a matrix of numbers of ICP elevations of different levels (20–40 mm Hg) and durations (0.5–20 min). In each case, the numbers of ICP elevations were standardized to 10 h of recording time, providing the opportunity for comparisons of ICP curves between individuals. Compared to the surgery group, there was a rather high number of ICP elevations of 20 mm Hg of various durations in the nonsurgery group, e.g. ICP elevations of 20 mm Hg lasting 10 min occurred in 13 of 19 children (68%) in the nonsurgery group. There was no apparent relationship between ICP and age or between the size of the cerebral ventricles and ICP. In children with hydrocephalus, the presentation of the ICP data as a matrix of ICP elevations of different levels and durations may enhance the informative value of continuous ICP monitoring, as compared to the calculation of mean ICP and visual detection of plateau waves.

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Section: Comparisons Of Icp In Patients Undergoing Surgery or Conservmentioning

confidence: 91%

Section: Quantitative Analysis Of Icpmentioning

confidence: 99%

Differences in Quantitative Characteristics of Intracranial Pressure in Hydrocephalic Children Treated Surgically or Conservatively

Eide¹,

Due-Tønnessen²,

Helseth³

et al. 2002

Pediatr Neurosurg

View full text Add to dashboard Cite

show abstract

“…In a study of children with cranisoynostosis aged 0–15 years, ICP before surgery increased with increasing age to reach a maximum at 6 years, and then it declined with increasing age [2]. Others have reported that in patients aged 20–88 years of age, pressure measured by lumbar puncture increased with increasing age [18]. In another study of patients with hydrocephalus aged 17–86 years, no significant relationship between age and ICP was found [19].…”

Section: Discussionmentioning

confidence: 99%

Assessment of Continuous Intracranial Pressure Recordings in Childhood Craniosynostosis

et al. 2002

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In this study, we explored two strategies of assessing continuous intracranial pressure (ICP) recordings in children with craniosynostosis, namely either by computation of the mean ICP or by computation of the accurate numbers of ICP elevations of different durations. The ICP recordings of 121 consecutive patients with a tentative diagnosis of craniosynostosis who underwent continuous ICP monitoring were examined. The relationship between mean ICP and numbers of ICP elevations was defined. The distribution of numbers of ICP elevations between patients either undergoing surgery or conservative treatment was also compared, since the choice of treatment was heavily dependent on the results of ICP monitoring. At the time of ICP monitoring, calculation of mean ICP was the main parameter for assessment of ICP curves. After a median observation period of 16 months, the ICP curves were reexamined by means of the software Sensometrics^TM Pressure Analyser, which presents the ICP curve as a matrix of numbers of ICP elevations of different levels (20–40 mm Hg) and durations (0.5– 20 min). Since the recording period differed between the cases, the numbers were standardized to a given recording time of 10 h, to allow for comparisons between patients. Cases with a borderline mean ICP during sleep (mean ICP 10–15 mm Hg) constituted 40.5% of the 121 patients. In this group, a rather weak relationship between mean ICP and the number of ICP elevations above 20 mm Hg was found, as well as a relatively high number of ICP elevations above 20 mm Hg of various durations. As compared to the patients undergoing surgery, a rather high number of ICP elevations above 20 mm Hg of various durations was found in patients undergoing conservative treatment. The study confirmed our hypothesis that in children with craniosynostosis, calculation of mean ICP does not describe the ICP curve in a reliable way. Decision-making should also include the computation of the distribution of numbers of ICP elevations, since this procedure represents a more sensitive strategy of detecting intracranial hypertension.

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“…A value below 13 mm Hg/(ml/min) characterises normal CSF circulation 41 ; above 18 mm Hg/(ml/min) the CSF circulation is clearly disturbed 42 ; between 13 mm Hg/ (ml/min) and 18 mm Hg/(ml/min) there is a grey zone, when other compensatory parameters and other clinical investigations should be considered to make a decision about shunting. Because the resistance to CSF outflow both in normal individuals 43 and in patients with normal pressure hydrocephalus (NPH) 44 increases with age, it is very likely that the ''critical threshold'' of normal and abnormal R CSF should be also age adjusted.…”

Section: Icp In Hydrocephalus and Benign Intracranial Hypertensionmentioning

confidence: 99%

Monitoring and interpretation of intracranial pressure

Czosnyka

Pickard²

2004

Journal of Neurology, Neurosurgery & Psychiatry

661

481

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Age dependency of resistance to cerebrospinal fluid outflow

Abstract: The present study shows a small but critical increase in Rout with increased patient age. A notable residual variation was present and borderline values of Rout should be regarded and used with caution.

Cited by 112 publications

References 19 publications

Differences in Quantitative Characteristics of Intracranial Pressure in Hydrocephalic Children Treated Surgically or Conservatively

Differences in Quantitative Characteristics of Intracranial Pressure in Hydrocephalic Children Treated Surgically or Conservatively

Assessment of Continuous Intracranial Pressure Recordings in Childhood Craniosynostosis

Monitoring and interpretation of intracranial pressure

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