Age at onset in patients with bipolar I and II disorder: a comparison of large sample studies

Age-at-onset and association with clinical features in bipolar inpatients: A case-records-based study from a tertiary hospital in eastern part of Nepal

“…3 In a review done to compare the difference between bipolar I and II disorders , the AAO of bipolar I disorder patients in studies from United States ranged from 18-21 years in most studies, around 24 years in United Kingdom or Canada, and around 28 years in China. 14 Our mean AAO of around 24 years seems to fall within the range, however, slightly earlier than as reported in Indian studies and later than American studies.…”

“…2 In a review done for AAO with both bipolar I and bipolar II disorders, AAO ranged from around 18 years to 30 years. 14 Studies done in India to study co-morbidity or phenomenology, course and outcome in bipolar disorder reported the mean AAO of around 27 years. 13,18 The median AAO was reported as 24 years (IQR 19-32) by Tondo et al 19 and 24 years (13.1) by another study.…”

“…3 However, a recent review has mentioned that AAO in 'North American samples was earlier than European samples and 10 years earlier than South American samples'. 14 Considering the lack of published data from this geographical area, this article is an attempt to report the mean AAO in admitted patients in a tertiary care hospital from eastern part of Nepal and to study the association of clinical variables with AAO.…”

Pharmacotherapeutic interventions for bipolar disorder type II: addressing multiple symptoms and approaches with a particular emphasis on strategies in lower and middle-income countries

“…This is a concern with a positive relationship seen between increasing urbanization and increasing number of suicides [88]. Prevalence rates for BD vary across countries with an estimated prevalence of more than 1% of the world's population [69,89,90] up to 5% [69,83,[91][92][93][94][95][96]. In their recent review, Clemente et al (2015) estimated that the pooled 1-year prevalence of BP-I was 0.71% (95%CI 0.56-0.86) principally among higher-income countries and 0.50% (95%CI 0.35-0.64) for BP-II [83].…”

Patterns in Psychiatrists’ Prescription of Valproate for Female Patients of Childbearing Age With Bipolar Disorder in Japan: A Questionnaire Survey

“…Bipolar disorder frequently emerges in the late teens and young adults (1)(2)(3) and its prevalence in males and females is the same (4). The nature, course, and prognosis of bipolar disorder include: (a) a tendency toward remission and recurrent mood episodes (5), (b) frequent comorbidities such as substance use and anxiety disorders (6), (c) decreased quality of life and neurocognitive functioning in various domains such as work and family life (7,8), and (d) high mortality characterized by suicide (9,10) and general medical conditions (11).…”