Age at ART initiation and proviral reservoir size in perinatal HIV-1 infection: considerations for ART-free remission
Soumia Bekka,
Kristen Kelly,
Mareike Haaren
et al.
Abstract:Purpose of review
Achieving ART-free remission without the need for lifelong antiretroviral treatment (ART) is a new objective in HIV-1 therapeutics. This review comprehensively examines the literature to evaluate whether the age at ART initiation in children with perinatal HIV-1influences the size and decay of the HIV-1 reservoir. The insights gathered from this review serve to inform the field on the unique dynamics of HIV-1 reservoir size in perinatal HIV-1 infection as a function of age at ART … Show more
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