Age- and sex-specific normal values for shock index in National Health and Nutrition Examination Survey 1999-2008 for ages 8 years and older

Rappaport, Lara; Deakyne, Sara; Carcillo, Joseph A.; McFann, Kim; Sills, Marion R.

doi:10.1016/j.ajem.2013.01.014

Cited by 38 publications

(35 citation statements)

References 26 publications

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“…This shows slightly better diagnostic values of ASI than actual SI. [6] Unlikely, no such significant differences were observed in the present study. SI has failed to show prognostic information among trauma victims in India, and variation among predictive values may not be beneficial.…”

contrasting

confidence: 89%

Distribution of shock index and age shock index score among trauma patients in India

Bhandarkar

Munivenkatappa

Roy

et al. 2017

Int J Crit Illn Inj Sci

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contrasting

confidence: 89%

Distribution of shock index and age shock index score among trauma patients in India

Bhandarkar

Munivenkatappa

Roy

et al. 2017

Int J Crit Illn Inj Sci

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“…Data were abstracted on donor demographics, hemodynamic parameters, use of vasopressors, cause of brain death, as well as whether the donor was felt to be a suitable candidate for cardiac donation (either procured or planned procurement that was not carried out due to the lack of a suitable recipient). Hemodynamic parameters were age adapted, as reported elsewhere 8 . In addition, echocardiography data was collected, including serial echocardiograms as available.…”

Section: Methodsmentioning

confidence: 99%

Cardiac Dysfunction Following Brain Death in Children

Krishnamoorthy

Borbely

Rowhani-Rahbar

et al. 2015

Pediatric Critical Care Medicine

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Background Cardiac dysfunction has been reported to occur in as much as 42% of adults with brain death, and may limit cardiac donation after brain death. Knowledge of the prevalence and natural course of cardiac dysfunction after brain death may help to improve screening and transplant practices but adequately sized studies in pediatric brain death are lacking. The aims of our study are to describe the prevalence and course of cardiac dysfunction after pediatric brain death. Methods We conducted a cross-sectional study using an organ procurement organization database (Life Center Northwest) of potential pediatric cardiac donors diagnosed with brain death between January 2011 and November 2013. Transthoracic echocardiograms (TTEs) were reviewed for cardiac dysfunction [defined as ejection fraction (EF) < 50% or the presence of regional wall motion abnormalities (RWMAs)]. Descriptive statistics were used to analyze clinical characteristics and describe longitudinal echocardiogram findings in a subgroup of patients. We examined for heterogeneity between cardiac dysfunction with respect to cause of brain death. Results We identified 60 potential pediatric cardiac donors (age ≤ 18 years) with at least one TTE following brain death. Cardiac dysfunction was present in 23 (38%) patients with brain death. Mean EF (37.6% vs. 62.2%) and proportion of procured hearts (56.5% vs. 83.8%) differed significantly between the groups with and without cardiac dysfunction, respectively. Of the 11 subjects with serial TTE data, the majority (73%) of patients with cardiac dysfunction improved over time, leading to organ procurement. No heterogeneity between cardiac dysfunction and particular causes of brain death was observed. Conclusion The frequency of cardiac dysfunction in children with brain death is high. Serial TTEs in patients with cardiac dysfunction showed improvement of cardiac function in most patients, suggesting that initial decisions to procure should not solely depend on the initial TTE exam results.

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“…Age and sex also were entered into the model as potential confounding factors. 24,25 Third, using multivariate Cox proportional hazards models with interaction terms, pooled analyses were conducted to determine whether SI was an independent risk factor of the other predictor variables in all study patients (Table 3). Fourth, generalized additive models were used to calculate the mean survival times (MSTs) for the given SI values.…”

Section: Resultsmentioning

confidence: 99%

Shock Index and Decreased Level of Consciousness as Terminal Cancer Patients' Survival Time Predictors: A Retrospective Cohort Study

Sato

Yokoi

Tsuneto

2016

Journal of Pain and Symptom Management

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Age- and sex-specific normal values for shock index in National Health and Nutrition Examination Survey 1999-2008 for ages 8 years and older

Cited by 38 publications

References 26 publications

Distribution of shock index and age shock index score among trauma patients in India

Distribution of shock index and age shock index score among trauma patients in India

Cardiac Dysfunction Following Brain Death in Children

Shock Index and Decreased Level of Consciousness as Terminal Cancer Patients' Survival Time Predictors: A Retrospective Cohort Study

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