Age and respiratory syncytial virus etiology in bronchiolitis clinical outcomes

Rodríguez‐Fernández, Rosa; González-Sánchez, María-Isabel; Pérez-Moreno, Jimena; González‐Martínez, Felipe; Navazo, Sara de la Mata; Mejías, Asunción; Ramilo, Octavio

doi:10.1016/j.jacig.2022.05.005

Cited by 8 publications

(5 citation statements)

References 33 publications

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“…Multivariable analysis showed that age <1 month and the need for HFNC support were independently associated with a worse clinical outcome, according to the literature [43,44]. In our setting, after the failure of low-flow oxygen administration, HFNC treatment represented a rescue therapy in bronchiolitis, permitting the treatment of moderate to severe bronchiolitis also in Pediatric Units in Spoke hospitals.…”

Section: Discussionsupporting

confidence: 55%

Management of Acute Bronchiolitis in Spoke Hospitals in Northern Italy: Analysis and Outcome

Guidi,

Ragusa,

Mussinatto

et al. 2024

Diseases

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Bronchiolitis is an acute viral infection of the lower respiratory tract that affects infants and young children. Respiratory syncytial virus (RSV) is the most common causative agent; however, other viruses can be involved in this disease. We retrospectively reviewed the clinical features of infants aged less than 12 months hospitalized for acute bronchiolitis in our Pediatric Units of Chivasso, Cirié, and Ivrea in Piedmont, Northern Italy, over two consecutive bronchiolitis seasons (September 2021–March 2022 and September 2022–March 2023). Patient-, disease-, and treatment-related variables were analyzed. The probability of therapeutic success (discharge home) was 96% for all patients (93% for RSV vs. 98% for non-RSV patients, p > 0.05). Among 192 patients, 42 infants (22%) underwent high-flow oxygen support (HFNC), and only 8 (4%) needed to be transferred to our hub referral hospital. Factors associated with hub hospital transfer were the age under 1 month and the failure of HFNC. The wide and increasing use of HFNC in pediatric inpatients improved the management of bronchiolitis in Spoke hospitals, reducing transfer to a hub hospital provided with Intensive Care Units.

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Section: Discussionsupporting

confidence: 55%

Management of Acute Bronchiolitis in Spoke Hospitals in Northern Italy: Analysis and Outcome

Guidi,

Ragusa,

Mussinatto

et al. 2024

Diseases

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show abstract

“…Multivariate analysis confirmed that age <1 month and the need of HFNC support were independently associated with a worse clinical outcome and a more frequent need for transfer to Hub hospital with a PICU or a NICU, according to literature [28,30].…”

Section: Discussionmentioning

confidence: 67%

Management of Acute Bronchiolitis in Spoke Hospitals: Analysis and Outcome

Guidi,

Ragusa,

Mussinatto

et al. 2023

Preprint

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Bronchiolitis is an acute viral infection of the lower respiratory tract that affects infants and young children. Respiratory syncytial virus (RSV) is the most common causative agent, however other viruses can be the reason of the disease. We retrospectively reviewed the clinical features of infants aged less than 12 months referred to our Pediatric Units of Chivasso, Cirié and Ivrea for acute bronchiolitis requiring hospitalization over two consecutive bronchiolitis seasons. Patient-, disease- and treatment related variables were analyzed in this retrospective study. We were able to show how with the high flow oxygen support (HFNC) only a very low number of children (8 out of 192) need to be trasferred to our HUB referral centers. The probability of success were 96% for all patients and 93% for RSV vs. 98% for non-RSV patients (P=NS). Factor associated to failure of treatment were age below 1 months and the failure of HFNC. The wide and increasing use of HFNC in pediatric inpatients improved management of bronchiolitis in Spoke hospitals, reducing transfer to a Hub hospital provided with Intensive Care Units.

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“…Although it is caused in most cases by the RSV or other viruses, there are several cases in which the etiology remains unknown 2 . The associated risk factors may also be essential in its development and prognosis 2,7,42 …”

Section: Discussionmentioning

confidence: 99%

Worldwide research trends on bronchiolitis in pediatrics

Nievas‐Soriano,

Martín‐Latorre,

Martín‐González

et al. 2023

Pediatric Pulmonology

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Background The COVID‐19 pandemic has led to a significant increase in cases of bronchiolitis among children. As a result, there has been a corresponding increase in the number of publications on this topic. It is essential to examine the main areas of focus within the scientific literature to understand the current trends in research on pediatric bronchiolitis. This research aims to analyze the types of scientific advances related to pediatric bronchiolitis, the research trends being pursued, and the countries and research institutions leading these efforts. By understanding these aspects of bronchiolitis research, we can better understand the current state of knowledge and identify areas where further research is needed. Methods To conduct a bibliometric analysis of the scientific literature on pediatric bronchiolitis, all relevant publications were retrieved from the Scopus database. The Scopus API and the SW VosViewer software with optimized modularity functions were used. This analysis was intended to provide a comprehensive overview of the current state of research on this topic, including the types of scientific advances being developed, the research trends being pursued, and the countries and research institutions leading these efforts. Results A total of 3810 publications were reviewed. We observed an increasing number of publications, particularly in recent years. Of these, 73.7% were articles, 95% were written in English, and 29.4% were from the United States. The main keywords used in these publications included: human, bronchiolitis, child, preschool, preschool child, major clinical study, controlled study, pneumonia, asthma, adolescent, hospitalization, infant, and newborn. These keywords were grouped into six clusters: outpatient management, long‐term consequences, etiology, intensive care management, diagnostic methods, and the main cluster, which focused on hospital treatment and clinical studies. Conclusions The bibliometric analysis of bronchiolitis research in pediatrics reveals that there has been a significant increase in the number of publications on this topic, particularly in recent years. Most of these publications are articles written in English and published in the United States. The main keywords used in these studies relate to various aspects of bronchiolitis, including diagnosis, treatment, and long‐term consequences. The results of this analysis suggest that bronchiolitis is a topic of significant interest and concern for researchers and practitioners in the field of pediatrics and that further research is needed to improve our understanding and management of this condition.

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Age and respiratory syncytial virus etiology in bronchiolitis clinical outcomes

Cited by 8 publications

References 33 publications

Management of Acute Bronchiolitis in Spoke Hospitals in Northern Italy: Analysis and Outcome

Management of Acute Bronchiolitis in Spoke Hospitals in Northern Italy: Analysis and Outcome

Management of Acute Bronchiolitis in Spoke Hospitals: Analysis and Outcome

Worldwide research trends on bronchiolitis in pediatrics

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