“…NUMEROUS INVESTIGATORS have reported age-related fine structural alterations in various organs of several insects (see Lamb, 1978;Sohal and McArthur, 1985;Sohal, 1985;Baker et al, 1985;Gartner, 1986). Some of these included flight muscle (Rockstein and Bhatnagar, 1965;Simon et al, 1969;Takahashi et al, 1970;Sohal and Allison, 1971;Sacktor and Shimada, 1972;Sohal et al, 1972;Sohal, 1976;Chesky, 1978;Shafiq, 1979, 1981;Collatz and Collatz, 1981;Economos et al, 1982), heart (Sohal, 1970(Sohal, , 1978Butch et al, 1970;Cruz-Landim, 1976;Collatz and Collatz, 1981), brain (Sohal and Donato, 1979;Collatz and Collatz, 1981;Kern and Wegener, 1984), midgut (Gartner, 1970(Gartner, , 1973Gartner and Gartner, 1976;Anton-Erxleben et al, 1983) and malpighian tubules (Miquel, 1971;Sohal and Lamb, 1979;Collatz and Collatz, 1981). Most of the alterations involved mitochondrial size and number, cytoplasmic and nuclear inclusions, and the accumulation of virus-like particles.…”