Age-adjusted charlson comorbidity index score as predictor of prolonged postoperative ileus in patients with colorectal cancer who underwent surgical resection

Abstract

Comorbidities had considerable effects on the development of postoperative ileus (POI). The primary aim of the present study was to determine the influence of the age-adjusted Charlson comorbidity index (ACCI) score on the risk of prolonged POI in patients with colorectal cancer who underwent surgical resection. Using the electronic Hospitalization Summary Reports, we identified 11,397 patients with colorectal cancer who underwent surgical resection from 2013 through 2015. Logistic regression models were applied to evaluate the effect of the ACCI score on the risk of prolonged POI. The ACCI score had a positive graded association with the risk of prolonged POI in both colon and rectal cancer (P for trend < 0.05). Among patients with rectal cancer, after adjusting for potential confounders, those with an ACCI score of 4–5 had a 108% higher risk of prolonged POI than those with an ACCI score of 0–1 (odds ratio [OR], 2.08; 95% confidence interval [CI], 1.09–3.98), and those with an ACCI score of ≥ 6 had a 130% higher risk (OR, 2.30; 95% CI, 1.08–4.89). Among patients with colon cancer, those with an ACCI score of ≥ 6 had a 47% greater risk of prolonged POI than those with an ACCI score of 0–1 (OR, 1.47; 95% CI, 1.07–2.02). These findings suggested that a higher ACCI score was an independent predictor of the development of prolonged POI.

CHA2DS2-VASc score as predictor of ischemic stroke in patients undergoing coronary artery bypass grafting and percutaneous coronary intervention

“…In addition, each diagnosis of disease and procedure in this study was made by ICD codes, which may cause bias from coding errors. However, the validity and reliability of this database have been proved in prior studies 32 , 33 . To minimize such potential confounding bias, we used the corresponding Chinese terms to check the identified diseases and procedures.…”

Cementless versus Cemented Fixation in Total Knee Arthroplasty: Usage, Costs, and Complications during the Inpatient Period

“…Patient demographics (age, gender, race, and insurance status) and hospital characteristics (rural, urban nonteaching, urban teaching, small bed size vs. large bed size, medium bed size vs. large bed size) were used as variables in predictive models. Charlson Comorbidity Index (CCI), [26][27][28][29] a validated predictor of inpatient mortality, hospital length of stay (LOS), 10-year mortality, and readmission, was used to assess patient preoperative health status. [30][31][32] Risk Factors and Adverse Events…”

Multivariate machine learning models for prediction of postoperative intestinal obstruction in patients underwent laparoscopic colorectal surgery: A retrospective observational study

“…In addition, a recent retrospective study involving 11,397 patients who underwent open or laparoscopic colectomy showed that the high age-adjusted Charlson comorbidity index score was an independent predictor of POI prolongation [19]. Long operating time was a risk factor for POI in colorectal surgery [20].…”