AGA Technical Review on Intragastric Balloons in the Management of Obesity

Shah, Raj; Dayyeh, Barham K. Abu; Saumoy, Monica; Murad, M. Hassan

doi:10.1053/j.gastro.2021.02.043

Cited by 23 publications

(13 citation statements)

References 94 publications

(157 reference statements)

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“…It also leads to improvement in metabolic syndrome, such as type 2 diabetes mellitus, hypertension, hypertriglyceridemia, and hepatic steatosis [8] with sustained results in a 1-year follow-up study [9]. However, as expected, its efficacy pales in comparison to other common laparoscopic bariatric surgeries, such as adjustable gastric band, sleeve gastrectomy, and Roux-en-Y gastric bypass (Figure 3) [7,10,11]. The most common side effects are abdominal pain, nausea and vomiting, and reflux [12].…”

Section: Discussionmentioning

confidence: 88%

“…IGB offers an average total weight loss of around 7-17 kg (% TWL: 7-15%; % EWL: 22-50%) [7] at time of removal, with maintenance of 7-9 kg (8-9% TWL; 29-33% EWL) [7] TWL at 1 year. It also leads to improvement in metabolic syndrome, such as type 2 diabetes mellitus, hypertension, hypertriglyceridemia, and hepatic steatosis [8] with sustained results in a 1-year follow-up study [9].…”

Section: Discussionmentioning

confidence: 99%

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Small Bowel Obstruction due to Migrated Intragastric Balloon: A Case Report and Literature Review

Tan

Fok

Nguyen

et al. 2022

Case Reports in Surgery

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Introduction. With the rising rate of obesity world-wide, there are increasing weight loss options including operative and non-operative techniques. Endoscopic intragastric balloons (IGB) have gained popularity since its inception three decades ago and is viewed as a less invasive alternative to bariatric surgery. However, complications, though rare and probably under-reported, can be associated with significant morbidity and mortality. Case Presentation. We present the case of a 44-year-old woman who presented with a two-day history of upper abdominal pain, nausea, and obstipation, on the background of a Spatz3™ Balloon (Spatz FGIA, Great Neck, NY, USA) endoscopically placed seven months prior. Computed tomography scan confirmed small bowel obstruction due to a migrated IGB, requiring laparotomy and enterotomy for retrieval. Conclusion. With the development of new types of IGB and increasing usage, it is important to monitor for issues and complications.

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Section: Discussionmentioning

confidence: 88%

Section: Discussionmentioning

confidence: 99%

Small Bowel Obstruction due to Migrated Intragastric Balloon: A Case Report and Literature Review

Tan

Fok

Nguyen

et al. 2022

Case Reports in Surgery

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“…Obesity is a well-known nutritional disorder and it is well-recognized as a contributor to many diseases (Klein et al, 2002;Shah et al, 2021). It is a condition where the body starts converting excessive free energy into loose adipose tissue (Luo and Liu, 2016).…”

Section: Discussionmentioning

confidence: 99%

Acute and sub-acute toxicity study of anti-obesity herbal granules in Sprague Dawley rats

Patel¹,

Shukla

Pande³

et al. 2024

Braz. J. Biol.

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Toxicological studies are essential for developing novel medications in pharmaceutical industries including ayurvedic preparation. Hence, the present study is aimed to evaluate acute and 28-days repeated dose oral toxicity of anti-obesity polyherbal granules (PHG) in Sprague Dawley rats by OECD guidelines No 425 and 407, respectively. In an acute oral toxicity study, a single dose of 2 g/kg PHG was administered to rats and mortality, body weight, and clinical observations were noted for fourteen days. However, in the subacute oral toxicity study, the PHG was administered orally at doses of 0.3, 0.5 and 1 g/kg daily for 28 days to rats. Food intake and body weight were recorded weekly. On the 29th day, rats were sacrificed and subjected to haematological, biochemical, urine, necropsy, and histopathological analysis. In an acute oral toxicity study, no treatment-related, mortality, behavioral changes, and toxicity were found throughout fourteen days. Likewise, in the sub-acute toxicity study, no mortality and toxic effects were found in haematology, biochemical, urine, necropsy and histopathological analysis in rats for 28 days of treatment with PHG. Based on these results, the LD50 of PHG was found to be greater than 2 g/kg and the no-observed-adverse-effect level (NOAEL) of PHG for rats was found to be 0.5 g/kg/day. Thus, anti-obesity polyherbal granules showed a good safety profile in animal studies and can be considered an important agent for the clinical management of obesity.

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“…More recently the American Gastroenterological Society has recommended using intragastric balloons as an adjunct therapy for patients with NAFLD, and this could also be considered. ( 38 ) Patients leave their consultation with a personalized management plan that summarizes dietary goals, exercise regimens, medications, and further referrals. Educational handouts augment programming.…”

Section: The Innovative Center For Health and Nutrition In Gastroente...mentioning

confidence: 99%

Multidisciplinary Clinic Models: A Paradigm of Care for Management of NAFLD

et al. 2021

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ultidisciplinary clinics (MDCs) are an emerging model of health care delivery, offering patients coordinated care services to diagnose problems early and develop cohesive treatment plans. MDCs are commonly used in oncology, (1) type 2 diabetes mellitus (T2DM), (2) and women's health, (3) where they improve patient satisfaction and clinical and financial outcomes. In this review, we examine current MDC models and share a framework for patients with NAFLD to guide development of future multidisciplinary NAFLD programs. Multidisciplinary Care Models in MedicineWhile traditional health care delivery models consist of physicians assessing patients independently, MDCs promote coordinated care by integrating consultations and centralizing into a single clinic space. MDCs are often seen in oncology practices where multiple consultations are coordinated by a navigator into a single visit. (4) Many also have weekly conferences involving multiple providers who discuss and coordinate management plans and follow-up. (4,5) These models promote evidence-based, patient-centered plans and have been shown to improve clinical outcomes. (5) For example, a single-day MDC for patients with liver cancer that features a central clinical coordinator and frequent team meetings reported improvement in diagnosis, treatment, patient-provider communication, and satisfaction. (6) Despite variations in structure, MDCs are also well received by patients. In traditional sequential referral models of care, patients perceive poorer physician communication, inefficient use of time, misdiagnosis, mistreatment, and decreased satisfaction, which can lead to seeking a second opinion. (7) Conversely, patients in MDCs enjoy improved patient-physician communication and increased efficiency of travel time, appointments, and testing. (4,8) MDCs also improve patient experience and quality of life in cancer care, while reducing health care costs. (9) Multidisciplinary Care in NAFLDThe complexity of NAFLD and its associations with metabolic disease, cardiac and diabetic complications, and lifestyle factors make it ideal for multidisciplinary care. Patients with metabolic syndrome are at high risk for developing NAFLD complications, such as cirrhosis and HCC. (10) Data also suggest

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AGA Technical Review on Intragastric Balloons in the Management of Obesity

Cited by 23 publications

References 94 publications

Small Bowel Obstruction due to Migrated Intragastric Balloon: A Case Report and Literature Review

Small Bowel Obstruction due to Migrated Intragastric Balloon: A Case Report and Literature Review

Acute and sub-acute toxicity study of anti-obesity herbal granules in Sprague Dawley rats

Multidisciplinary Clinic Models: A Paradigm of Care for Management of NAFLD

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