African mistletoe (Loranthaceae) ameliorates cholesterol-induced motor deficit and oxidative stress in adult BALB/c mice

Oremosu, A.A.; Edem, Edem Ekpenyong; Dosumu, Olufunke O.; Osuntoki, A.A

doi:10.4103/jeca.jeca_27_17

Cited by 3 publications

(3 citation statements)

References 14 publications

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“…Among the constituents of V. album , besides microProteins [ 148 ], other constituents, i.e., phenols and in particular flavonoids, have been considered responsible for this activity [ 36 , 143 , 149 , 150 ], in consideration of their well-known anti-ROS and radical-scavenger properties [ 151 ], and of the isolation of new flavonoids in V. album [ 152 , 153 ]. Most of the studies amplified the research to other constituents to evidence how they may co-operate in the activity [ 149 , 150 , 151 , 152 , 153 , 154 , 155 , 156 ], including new phenolic compounds isolated from the whole plant [ 157 ]. In several papers, more activities are considered on the basis of a connection made between inflammation and many related pathologies [ 157 , 158 , 159 , 160 , 161 , 162 , 163 , 164 , 165 , 166 , 167 , 168 , 169 , 170 ].…”

Section: Introductionmentioning

confidence: 99%

The Anti-Inflammatory Activity of Viscum album

Nicoletti

2023

Plants

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The therapeutic story of European mistletoe (Viscum album L.) presents a seesawing profile. In ancient times, this hemiparasitic plant was considered a panacea and even to be endowed with exceptional beneficial properties. In more recent times, despite its multiple uses in traditional medicines, some parts of the plant, in particular the berries, were considered poisonous and dangerous, including concerns of cytotoxicity, which spread serious suspicion on its medicinal utility. However, since the last century, medical interest in mistletoe has come back in force due to its utilization in clinical cancer treatments, based on its selective action on tumor cells. In Central Europe, the hydro-alcoholic extracts of European mistletoe register a relevant and continuous utilization in anthroposophic medicine, which is a holistic system that includes the utilization of phytomedicinal substances. In Switzerland and Germany, most physicians and patients use these products as complementary therapy in oncological treatments. However, despite its increasing use in this field, the results of mistletoe’s use are not always convincing, and other aspects have appeared. Nowadays, products that contain mistletoe are utilized in several fields, including diet, phytotherapy, veterinary medicine and homeopathy, but in particular in cancer therapies as coadjuvant factors, in consideration of several positive effects including effects in the improvement of quality-of-life conditions and reinforcement of the immune system. In this review, based on the understanding of the association between cancer and inflammation, we propose a relationship between these recent uses of mistletoe, based on its antioxidant properties, which are supported by phytochemical and pharmacological data. The unicity of mistletoe metabolism, which is a direct consequence of its hemiparasitism, is utilized as a key interpretation element to explain its biological properties and steer its consequent therapeutic uses.

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Section: Introductionmentioning

confidence: 99%

The Anti-Inflammatory Activity of Viscum album

Nicoletti

2023

Plants

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“…The parallel bar test was employed to evaluate the impacts of tiger nut and coconut- enriched diets following DDVP exposure on motor coordination in mice. The test was conducted as previously reported [4] , [96] using two metal rods, each 1 m long and 2 mm thick. The two rods (equidistant to each other cm apart).…”

Section: Methodsmentioning

confidence: 99%

Tiger nut/coconut dietary intervention as antidotal nutritional remediation strategy against neurobehavioural deficits following organophosphate-induced gut-brain axis dysregulation in mice

Enye,

Edem,

Onyeogaziri

et al. 2024

Toxicology Reports

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“…Following the phytocomplex approach, in several papers, more research is considered [ 63 ] on the connection made between oxidative stress, inflammation, and many related pathologies [ 64 ], in particular, the hypoglycemic effects [ 65 , 66 ]. The antioxidant activity of Viscum extracts has been associated with hypoglycaemia, considering the important role played by oxidative stress in tissue damage by hypoglycaemia and diabetes [ 67 , 68 , 69 , 70 , 71 ], which may be the result of the deterioration in glucose homeostasis caused by metabolic disorders.…”

Section: The European Mistletoementioning

confidence: 99%

The Antioxidant Activity of Mistletoes (Viscum album and Other Species)

Nicoletti

2023

Plants

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In addition to the European mistletoe, Viscum album, which is the most known and utilized one, there are several species commonly known as mistletoe. They are spread in various regions of the planet and are all characterized by hemiparasitism and epiphytic behaviour. The published studies evidence other similarities, including the sharing of important biological properties, with the common presence of antioxidant effects. However, whereas the European mistletoe is largely utilized in medical treatments, although with controversial aspects, the scientific knowledge and medical uses of other mistletoes are still insufficient. This review focuses on the controversial medical story of European mistletoe regarding its antioxidant activity and the potentiality of the other species named mistletoe pertaining to botanical families and genera different from Viscum.

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African mistletoe (Loranthaceae) ameliorates cholesterol-induced motor deficit and oxidative stress in adult BALB/c mice

Cited by 3 publications

References 14 publications

The Anti-Inflammatory Activity of Viscum album

The Anti-Inflammatory Activity of Viscum album

Tiger nut/coconut dietary intervention as antidotal nutritional remediation strategy against neurobehavioural deficits following organophosphate-induced gut-brain axis dysregulation in mice

The Antioxidant Activity of Mistletoes (Viscum album and Other Species)

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