Aetiology, clinical features and treatment outcome of Intrauterine adhesion in Ilorin, Central Nigeria

Abiodun, Olusanya; Balogun, OR; Fawole, Adegboyega A

doi:10.4314/wajm.v26i4.28330

Cited by 14 publications

(16 citation statements)

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“…[7][8][9] Majority of the patients with intrauterine adhesion were within the ages of 25-39 years. This was similar to findings from studies carried out in other parts of Nigeria.…”

Section: Discussionmentioning

confidence: 99%

“…This was similar to findings from studies carried out in other parts of Nigeria. [6][7][8][9][10][11]13 The majority of the women were of low parity as in the studies carried out in Lagos and Federal capital Teritery, Nigeria and this shows that intrauterine adhesion can be associated with infertility. 6,20 The incidence of intrauterine adhesion was higher among women with tertiary level of education.…”

Section: Discussionmentioning

confidence: 99%

“…[7][8][9] The condition is usually caused by trauma to the basalis layer of the endometrium which is almost always related to a pregnancy event or following infection. 10,11 Dilatation and curettage of a recently pregnant uterus is a common aetiology of IUA in developing countries as well as Puerperal sepsis, schistosomiasis and genital tuberculosis.…”

Section: Introductionmentioning

confidence: 99%

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Outcome of intrauterine adhesion management at a Nigerian tertiary hospital: a five-year review

Opadiran

Isah

Agida

et al. 2018

Int J Reprod Contracept Obstet Gynecol

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Background: Intrauterine adhesion is a cause of menstrual abnormalities and infertility, which are leading complaints in gynaecological practice in Nigeria. Determining the aetiology and management option would help reduce this problem. The objective of this study was to determine the aetiology, mode of presentation, management option and outcome of intrauterine adhesionsMethods: A retrospective analysis of intrauterine adhesions at the University of Abuja Teaching Hospital over a five-year period from 2012 to 2016 was carried out. The case notes of the patients were retrieved from the records department and information extracted from these case notes using a questionnaire included the age, level of education, marital status, parity, complaints, predisposing factors, method of diagnosis, treatment method and outcome. Additional information was obtained from the theatre registered. The least follow up period was one year.Results: There were 82 patients diagnosed with Intrauterine Adhesion over the study period giving an incidence of 1.6%. Fifty-nine case notes were available for analysis. The case note retrieval rate was 72%. Majority of the patients were between the age range of 30-34 years (21, 35.6%). Those with tertiary level of education constituted the majority (34, 57%). Nullipara constituted 54.2% (32) of the total population. Menstrual abnormalities were the most common complaint with 93.2% and this includes those with menstrual abnormalities and other complaints. The commonest predisposing factor identified was a history of dilatation and curettage or uterine evacuation (28, 47.5%). Majority of the patients had partial intrauterine adhesions (51, 86.4%). All patients were treated with adhesiolysis, Foleys catheter insertion and hormonal therapy for 3 cycles. There was not statistical significance between those who had blind adhesiolysis and hysteroscopic adhesiolysis in terms of outcome. Restoration of menstrual flow was in 25, (42.4%) while 3, (5.1%) had miscarriges and an equal no of patients had term delivery.Conclusions: Dilatation and curettage is still a major predisposing factor in the development of intrauterine Adhesions. Blind adhesiolysis still has its place in the management of intrauterine adhesion in developing countries.

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“…[7][8][9] Majority of the patients with intrauterine adhesion were within the ages of 25-39 years. This was similar to findings from studies carried out in other parts of Nigeria.…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Outcome of intrauterine adhesion management at a Nigerian tertiary hospital: a five-year review

Opadiran

Isah

Agida

et al. 2018

Int J Reprod Contracept Obstet Gynecol

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show abstract

“…In some parts of this belt, infertility is said to constitute up to 65% of gynecological consultations [10]. Institution based incidence of infertility recently reported from some parts of Nigeria are: 4.0% [11], 11.2% [12] and 48.1% [13] respectively from llorin (North central), Abakaliki (south-east) and Oshogbo (South west).…”

Section: Introductionmentioning

confidence: 99%

“…While primary infertility is higher in other regions of the world, secondary infertility is more common in Africa [3]. In sub-Saharan Africa, pelvic infections largely constitute the cause of infertility in several places [9][10][11][12][13]. These stem from sexually transmitted diseases, post abortion and post-delivery complications.…”

Section: Introductionmentioning

confidence: 99%

Patterns and Management Challenges of Infertility in a LowResource Setting: A Prospective Cohort Study

2019

ARC Journal of Gynecology and Obstetrics

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However, the incidence varies from one region of the world to the other, being highest in the socalled infertility belt Abstract Objectives: To determine patterns and treatment outcomes of infertility among couples presenting with infertility in low-resource setting.Methods: A prospective cohort study of infertile women managed at Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria over a one-year period. Couples were followed up for a minimum of one year. Primary outcome measures were type/cause of infertility and conception rate. Univariate logistic regression was used to analyze data. Statistical significance was accepted when P-value is <0.05.Results: During the study, 126 of 419 new patients managed were cases of infertility, giving an incidence of 30.1%. Mean duration of infertility was 4.1±3.9years. The ratio of primary to secondary infertility was 1:3, and maternal age, socio-economic status and infertility duration did not significantly influence the type of infertility (p>0.05). Up to 55.6% (70/126) women had prior usage of herbal concoctions for infertility and was significantly influenced by infertility duration (p<0.001). Conception rate was significantly more following ovulation factor infertility (p< 0.001). Up to 29.3% of couples achieved pregnancy within one-year follow-up. Conclusion:The ratio of primary to secondary infertility was 1:3. Women with secondary infertility had significantly more conception rate. Overall, conception rate of 29.3% were achieved within one year of follow-up.

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Ethanol-induced male infertility: Effects of aqueous leaf extract ofTetracarpidium conophorum

et al. 2017

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This study investigated the effects of Tetracarpidium conophorum leaf extract on infertility induced by ethanol in male rats. Thirty rats were randomly divided into six groups of five animals each: Group 1 (positive control) received 0.9% saline only; Group 2 (ethanol alone) were given only 30% ethanol orally at 7 ml/kg body weight per day, thrice in a week; groups 3, 4 and 5 were given ethanol and co-treated with 50, 500 and 1,000 mg/kg body weight of leaf extract, respectively, while Group 6 was given ethanol and co-treated with a fertility drug, clomiphene citrate. Ethanol treatment resulted in significant (p < .05) decrease in LDH activity, G-6PDH activity, glycogen content, 3β and 17β HSD activities and testicular and epididymal Zn and Se contents and furthermore decrease in testicular sperm count, viability and marked increment in total sperm abnormalities, rate of sperm analysis parameters and consequently decreased reproductive hormone levels. Interestingly, co-administration of ethanol with either T. conophorum extract or drug almost ameliorated the toxic assault imposed by ethanol on reproductive organs and improved seminal qualities of the rats.

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Aetiology, clinical features and treatment outcome of Intrauterine adhesion in Ilorin, Central Nigeria

Cited by 14 publications

References 0 publications

Outcome of intrauterine adhesion management at a Nigerian tertiary hospital: a five-year review

Outcome of intrauterine adhesion management at a Nigerian tertiary hospital: a five-year review

Patterns and Management Challenges of Infertility in a LowResource Setting: A Prospective Cohort Study

Ethanol-induced male infertility: Effects of aqueous leaf extract ofTetracarpidium conophorum

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