Aetiology and pathology of otitis media with effusion in adult life

Mills, R; Hathorn, Iain

doi:10.1017/s0022215116000943

Cited by 45 publications

(36 citation statements)

References 50 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…1 This complements nicely recent articles by Wasson and Yung 2 on the evidence-based management of otitis media (in its various forms) and the study from Dundee of sinonasal symptoms in patients with ear disease 3 which confirmed the association between the two groups of conditions. The pathology of OME in children is far from clear, and as Mills and Hathorn point out, the situation in adults is no better, with many important gaps in our knowledge.…”

supporting

confidence: 70%

Glue ear in adults, paediatric sleep apnoea and the nose in exercise

Fisher¹,

Youngs²,

Hussain³

et al. 2016

J. Laryngol. Otol.

View full text Add to dashboard Cite

supporting

confidence: 70%

Glue ear in adults, paediatric sleep apnoea and the nose in exercise

Fisher¹,

Youngs²,

Hussain³

et al. 2016

J. Laryngol. Otol.

View full text Add to dashboard Cite

“…Furthermore, studies on nasal aerodynamics have shown that nasal resistance is significantly increased during nasal obstruction and that oral breathing can cause negative pressure in the nasopharynx and further negative pressure in the middle ear, which could aggravate ETD [ 27 ]. Similarly, nasal obstruction is also the most frequent nasal symptom in adult otitis media with effusion, which is considered closely related to ETD [ 28 , 29 ].…”

Section: Discussionmentioning

confidence: 99%

Eustachian tube dysfunction in patients with house dust mite-allergic rhinitis

Liang

Tian

et al. 2020

Clin Transl Allergy

View full text Add to dashboard Cite

Background One of the important pathogeneses of eustachian tube dysfunction (ETD) is nasal inflammatory disease. The prevalence of allergic rhinitis (AR) in adults ranges from 10 to 30% worldwide. However, research on the status of eustachian tubes in AR patients is still very limited. Methods This prospective controlled cross-sectional study recruited 59 volunteers and 59 patients with AR from Sun Yat-sen Memorial Hospital. Visual analogue scale (VAS) scores for AR symptoms and seven-item Eustachian Tube Dysfunction Questionnaire (ETDQ-7) scores were collected for both groups. Nasal endoscopy, tympanography and eustachian tube pressure measurement (tubomanometry, TMM) were used for objective assessment. All AR patients underwent 1 month of treatment with mometasone furoate nasal spray and oral loratadine. Then, the nasal condition and eustachian tube status were again evaluated. Results TMM examination revealed that 22 patients (39 ears, 33.1%) among the AR patients and 5 healthy controls (7 ears, 5.9%) had abnormal eustachian pressure. Twenty-two AR patients (37.3%) and 9 healthy controls had an ETDQ-7 score ≥ 15. With regard to nasal symptoms of AR, the VAS scores of nasal obstruction were correlated with the ETDQ-7 scores, and the correlation coefficient was r = 0.5124 ( p < 0.0001). Nasal endoscopic scores were also positively correlated with ETDQ-7 scores, with a correlation coefficient of 0.7328 ( p < 0.0001). After 1 month of treatment, VAS scores of nasal symptoms, endoscopic scores and ETDQ-7 scores were significantly decreased in AR patients ( p < 0.0001), and TMM examination also suggested that eustachian tube function was significantly improved after treatment ( p < 0.0001). Conclusions AR patients, especially those with severe nasal obstruction, could have ETD. The local conditions of the pharyngeal orifices of the eustachian tubes are closely related to the symptoms of ETD. After treatment with nasal glucocorticoids and oral antihistamines, eustachian tube function can significantly improve as nasal symptoms subside. Trial registration Chinese Clinical Trial Registery (ChiCTR2000029071) Registered 12 January 2020—Retrospectively registered, http://www.chictr.org.cn/edit.aspx?pid=48328&htm=4

show abstract

“…The optimal treatment plan is still being elucidated but currently involves topical and systemic steroids, use of antibiotics (where indicated), and in some severe cases, anti-IgE treatment such as omalizumab [30]. Control of underlying systemic pulmonary disease and/or aspirin desensitization can have a role for some patients [32,39]. Removal of polyps may be indicated in some cases but other traditional surgical approaches are unlikely to control symptoms for long.…”

Section: Treatmentmentioning

confidence: 99%

Idiopathic, Infectious and Reactive Lesions of the Ear and Temporal Bone

Magliocca

Vivas

Griffith

2018

Head and Neck Pathol

View full text Add to dashboard Cite

A number of infectious, inflammatory and idiopathic lesions develop within otologic tissues that may share similar clinical and/or microscopic features. This review first provides a working classification for otitis externa, and then otitis media and includes two recently described entities, eosinophilic otitis media and otitis media with ANCA-associated vasculitis. Next, the microscopic findings of a spectrum of otopathologic conditions are described, including post-inflammatory conditions such as tympanosclerosis and aural polyps, an overview of animate aural foreign body as well as iatrogenic aural foreign body reactions. Finally, a review of fungal disease affecting the ear with a brief synopsis of Candida auris, a recently described and virulent organism, is presented.

show abstract

Aetiology and pathology of otitis media with effusion in adult life

Cited by 45 publications

References 50 publications

Glue ear in adults, paediatric sleep apnoea and the nose in exercise

Glue ear in adults, paediatric sleep apnoea and the nose in exercise

Eustachian tube dysfunction in patients with house dust mite-allergic rhinitis

Idiopathic, Infectious and Reactive Lesions of the Ear and Temporal Bone

Contact Info

Product

Resources

About