Aerosol direct fluorination: syntheses of perfluoro ketones

Special applications of fluorinated organic compounds

“…helium, argon, nitrogen [32][33][34]. Of the similar importance is the fluorination in a liquid phase in the liquefied anhydrous hydrogen fluoride or 65 wt.% aqueous HF solution [35], perfluoroalkanes [36], and in low temperatures in R-11 freon [37].…”

Preparation of Highly Fluorinated Compounds

“…Primary and secondary amines give NF 2 and NF compounds respectively and fluorination of sulphur compounds gives products in which the sulphur has been oxidised to its maximum valency state of six [149] (Table 2.4). Perfluorinations of many ethers [155], cryptands [156], polyethers [119,157], including the largest perfluoro-macrocycle [158], perfluoro [60]-crown-20 [123,159], and the first perfluorinated sugar [160], orthocarbonates [161,162], ketones [163,164], esters [124,165], phosphanes [166] and alkyl halides [167,168] have been successfully accomplished by the LaMar or aerosol processes ( Perfluorinations of many ethers [155], cryptands [156], polyethers [119,157], including the largest perfluoro-macrocycle [158], perfluoro [60]-crown-20 [123,159], and the first perfluorinated sugar [160], orthocarbonates [161,162], ketones [163,164], esters [124,165], phosphanes [166] and alkyl halides [167,168] have been successfully accomplished by the LaMar or aerosol processes ( …”

Aerosol direct fluorination. Synthesis of perfluoroadamantane, the penultimate step

“…to alkanes, ethers, cycloalkanes, ketals, and ketones has been demonstrated. 1,2 We report here the extension of the process to the synthesis of perfluoroadamantane via direct fluorination of adamantane, a feat not realized by other direct fluorination methods nor by indirect fluorination methods to any significant degree.…”