Aerobic fitness in patients with fibrositis. A controlled study of respiratory gas exchange and ¹³³xenon clearance from exercising muscle

Abstract

Aerobic fitness was evaluated in 25 women with fibrositis, by having them exercise to volitional exhaustion on an electronically braked cycle ergometer. Compared with published standards, >80% of the fibrositis patients were not physically fit, as assessed by maximal oxygen uptake. Compared with matched sedentary controls, fibrositis patients accurately perceived their level of exertion in relation to oxygen consumption and attained a similar level of lactic acidosis, as assessed by their respiratory quotient and ventilatory threshold. Exercising muscle blood flow was estimated by '33xenon clearance in a subgroup of 16 fibrositis patients and compared with that in 16 matched sedentary controls; the fibrositis patients exhibited reduced '"xenon clearance. These results indicate a need to include aerobic fitness as a matched variable in future controlled studies of fibrositis and suggest that the "detraining phenomenon" may be of relevance to the etiopathogenesis of the disease.Fibrositis remains a perplexing enigma; apart from semiobjective findings of tender points, the physical examination findings are normal, and there is no acceptable pathophysiologic explanation for the symp-

Benefícios dos exercícios físicos na fibromialgia

“…Estes pacientes, caracteristicamente exibem diminuição da aptidão cardiorrespiratória (3,4) . Há evidência de que a atividade física modula a dor em pacientes com FM.…”

Searching for the cause of fibromyalgia: is there a defect in energy metabolism?

“…Recently it has become even more attractive to speculate that an abnormality of energy metabolism in skeletal muscle might underlie the condition. Evidence in support of that hypothesis was provided by the work of Bengtsson et a1 (12), Lund et a1 (13), and Bennett et a1 (14). Bengtsson and colleagues measured energy metabolites in biopsy specimens from tender points of trapezius and nontender sites of anterior tibialis muscles from patients with primary fibromyalgia and from controls.…”

Aplicación del ejercicio físico como terapia en medicina del trabajo para pacientes con fibromialgia

“…Numerosos autores consideran la capacidad aeróbica como uno de los factores determinantes en la patogénesis de la FM y hay evidencias de que al ejercitarse podemos modular el dolor en estos pacientes 26,43 . Aunque Bennett 43 encontró que el 80% de los pacientes presentaba bajo nivel de condición física, Sietsema 44 no encontró diferencias entre pacientes con FM y sujetos control usando para ello el VO 2pico y VO 2VT 26 .…”

“…Aunque Bennett 43 encontró que el 80% de los pacientes presentaba bajo nivel de condición física, Sietsema 44 no encontró diferencias entre pacientes con FM y sujetos control usando para ello el VO 2pico y VO 2VT 26 . En nuestro estudio hemos encontrado diferencias significativas entre individuos con distinto nivel de afectación atendiendo a su VO 2pico .…”

“…Los valores obtenidos en este estudio, son algo inferiores a los reflejados por Meiworm 45 aunque similares a los valores medios encontrados por otros autores 43,44 . Sin embargo, todos estos datos contrastan con los experimentados por nuestro grupo 2, con mayor nivel de afectación (22,1 ± 2,5 ml·kg…”