Aerobic degradation of ibuprofen in batch and continuous reactors by an indigenous bacterial community

Fortunato, María Susana; Abril, Nancy Piedad Fuentes; Martinefski, Manuela; Trípodi, Valeria; Papalia, Mariana Andrea; Radice, Marcela; Gutkind, Gabriel; Gallego, Alfredo; Korol, S.

doi:10.1080/09593330.2016.1156773

Cited by 24 publications

(6 citation statements)

References 51 publications

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“…Ascomycetes (Aspergillus nidulans, Eurotium amstelodami, Bipolaris tetramera), basidiomycetes (Bjerkandera sp., Phanerochaete chrysosporium, Trametes versicolor, Ganoderma lucidum, Irpex lacteus), and individual strains of Gram-negative bacteria (Variovorax sp., Sphingomonas sp.) and Gram-positive bacteria (Bacillus thuringiensis), microbial consortia (active sludge, soil and water consortia) as well as algae (Navicula sp., Chlorella sorokiniana, C. pyrenoidosa) were reported as IBP biodegraders [30,65,[71][72][73][74][75][76][77][78]. In addition, single cases of monocultures of bacteria capable of effective IBP bioconversion have been reported.…”

Section: Plos Onementioning

confidence: 99%

Response of Rhodococcus cerastii IEGM 1278 to toxic effects of ibuprofen

et al. 2021

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The article expands our knowledge on the variety of biodegraders of ibuprofen, one of the most frequently detected non-steroidal anti-inflammatory drugs in the environment. We studied the dynamics of ibuprofen decomposition and its relationship with the physiological status of bacteria and with additional carbon and energy sources. The involvement of cytoplasmic enzymes in ibuprofen biodegradation was confirmed. Within the tested actinobacteria, Rhodococcus cerastii IEGM 1278 was capable of complete oxidation of 100 μg/L and 100 mg/L of ibuprofen in 30 h and 144 h, respectively, in the presence of an alternative carbon source (n-hexadecane). Besides, the presence of ibuprofen induced a transition of rhodococci from single- to multicellular lifeforms, a shift to more negative zeta potential values, and a decrease in the membrane permeability. The initial steps of ibuprofen biotransformation by R. cerastii IEGM 1278 involved the formation of hydroxylated and decarboxylated derivatives with higher phytotoxicity than the parent compound (ibuprofen). The data obtained indicate potential threats of this pharmaceutical pollutant and its metabolites to biota and natural ecosystems.

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Section: Plos Onementioning

confidence: 99%

Response of Rhodococcus cerastii IEGM 1278 to toxic effects of ibuprofen

et al. 2021

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“…Carballa et al [45] obtained removal percentages of IBU around 40 % using an anaerobic activated sludge system; Nakada et al [46] achieved 90 % of IBU removal during activated sludge treatment; and Langenhoff et al [34] obtained the complete removal of IBU, in 4 days, using activated sludge from a pilot plant treating hospital wastewater. The aerobic degradation of IBU by an indigenous bacterial community was tested by Fortunato et al [47]. These authors found removal percentages around 99 % (33 h, 100 mg L -1 initial concentration), proving the ability of the indigenous communities to improve the treatment of wastewaters containing IBU.…”

Section: Ibuprofen and Paracetamol Removal Performance By Activated Sludge And Comparison With Adsorption Processesmentioning

confidence: 99%

Degradation of widespread pharmaceuticals by activated sludge: Kinetic study, toxicity assessment, and comparison with adsorption processes

Quintelas

Mesquita

Torres

et al. 2020

Journal of Water Process Engineering

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The growing presence of pharmaceutical compounds in aqueous systems leads to the search for new efficient and eco-friendly solutions to this problem. Although pharmaceutical products are widely found in the aqueous environments, there is limited understanding of their ecological effects. To augment the removal of pharmaceuticals, a bench reactor was inoculated with activated sludge and fed with a synthetic medium. Two pharmaceuticals of widespread usage, ibuprofen (IBU) and paracetamol (PARA) in the range 0.4-1 mg L -1 were used. The uptake values increased from 0.192 to 0.660 mg g -1 for IBU and from 0.104 to 0.341 mg g -1 for PARA. The removal efficiency reached values from 99.1-99.5 % and is independent of the initial IBU concentration. For PARA the removal percentage ranged from 93.3-98.8 decreasing with the increase on the initial concentration. The removal mechanism is well described by pseudo-first order and pseudo-second order kinetic models for all concentrations tested. At same time, batch assays were performed in order to assess the toxicity of both pharmaceuticals into the activated sludge using quantitative image analysis (QIA). For IBU experiments, QIA studies showed that this compound favors the growth of aggregated biomass rather than filamentous bacteria. A comparison between this biological technology and adsorption by a commercial porous ceramic material and Pinus bark was also performed. The results showed that the biological technology allowed better results (99.5 % against 19.4 and 9.3 %, respectively for the ceramic material and Pinus bark) for IBU. The results obtained for PARA showed comparable results for the biological technology and for adsorption by the ceramic material. The activated sludge system presented here appears to be a promising treatment for pharmaceutical contaminated effluents and the biomass present in the activated sludge seems do not be negatively affected by the presence of high concentrations of both pharmaceuticals.

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“…> 90%. Fortunato et al [39] performed the biodegradation study of ibuprofen with the indigenous bacterial community.…”

Section: Bacterial Community Associated With Pharmaceuticals Removalmentioning

confidence: 99%

Dynamics of bacterial community at varying sludge retention time within membrane bioreactor treating synthetic hospital wastewater

Tiwari¹,

Sellamuthu

Piché-Choquette

et al. 2021

Syst Microbiol and Biomanuf

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The study was conducted to investigate the effect of sludge retention on bacterial community composition of membrane bioreactor (MBR) treating synthetic hospital wastewater. The removal of four pharmaceuticals, namely carbamazepine, estradiol, venlafaxine, and ibuprofen in MBR, was studied at varying sludge retention time (SRT) duration of 100, 45, and 15 days and hydraulic retention time (HRT) of 18 h. The removal of ibuprofen and estradiol was constant at varying SRT; however, a negligible removal of carbamazepine and low removal of venlafaxine was observed (< 20%). The study suggested that the SRT of 45 days in MBR could provide maximum treatment efficiency via decreasing membrane clogging. The effect of sludge age and pharmaceutical presence on the bacterial community was investigated via high-throughput sequencing. The study reveals that the variation in SRT affects the dynamics of the bacterial community significantly. For instance, the dominant bacterium Caldimonas of SRT 100 was disappeared at lower SRTs. Moreover, the profile of the dominant genus of the SRTs varied greatly from each other.

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Aerobic degradation of ibuprofen in batch and continuous reactors by an indigenous bacterial community

Cited by 24 publications

References 51 publications

Response of Rhodococcus cerastii IEGM 1278 to toxic effects of ibuprofen

Response of Rhodococcus cerastii IEGM 1278 to toxic effects of ibuprofen

Degradation of widespread pharmaceuticals by activated sludge: Kinetic study, toxicity assessment, and comparison with adsorption processes

Dynamics of bacterial community at varying sludge retention time within membrane bioreactor treating synthetic hospital wastewater

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