Aerobic bacteriology of Chronic Suppurative Otitis Media (CSOM) in a tertiary care hospital: A retrospective study

Abstract

The present study was carried out to determine the aerobic microorganisms involved and their antibiotic sensitivity pattern in patients with Chronic Suppurative Otitis Media (CSOM) and to provide a guideline for empirical antibiotic therapy.Between March 2009 to February 2011, the ear discharge samples submitted at the microbiology laboratory were processed aerobically and all the isolates were included in this study. All organisms were identified morphologically and biochemically by standard laboratory procedures and antibiotic susceptibility pattern was determined by modified Kirby Bauer disc diffusion method as per National Committee for Clinical Laboratory Standard recommendations.Out of a total of 214 samples, microbiological culture was yielded from 202 (94.3%) specimens. Single organism were isolated from 168 (78.5%) of the culture positive specimens, while the remaining 34 (15.9%) had two or more organisms isolated. Pseudomonas aeruginosa 59 (35.1%) was the most common isolate, followed by Staphylococcus aureus 42 (25.0%) including 5 (3%) of the Methicillin Resistant Staphylococcus Aureus (MRSA). Antibiotic sensitivities of Pseudomonas aeruginosa showed that 93.2% isolates were sensitive to tobramycin, whereas, 91.5% isolates were sensitive to ceftazidime and 77.9% to amikacin.Only 50.8% of the isolates of Pseudomonas aeruginosa were sensitive to ciprofloxacin and 25.4% to gentamicin.For Staphylococcus aureus (other than MRSA) 95.2% were sensitive to cloxacillin, 83.3% to gentamicin and 78.5% to erythromycin. Only 07.1% were sensitive to ampicillin and 26.1% to ciprofloxacin.Pseudomonas aeruginosa was the most common isolate followed by Staphylococcus aureus. More than 90% of Pseudomonas and 90% of Staph aureus were sensitive to tobramycin and cloxacillin respectively. Therefore, these two drugs may be included in the formulary to cover the most common aerobic isolates involved in CSOM.

Bacteriological and Mycological profile of Chronic Suppurative Otitis Media among patients visiting Dhulikhel Hospital

“…In the present study S. aureus the most predominated organism had high sensitivity toward cloxacillin and gentamycin. The result is similar to the restrospective study carried out in Bharatpur, Nepal [29]. Of the S. aureus isolated, 4(6.67%) were methicillin resistant which was similar with the result of Iqbal et al [22].…”

Aspergillus fumigatus carrying TR34/L98H resistance allele causing complicated suppurative otitis media in Tanzania: Call for improved diagnosis of fungi in sub-Saharan Africa

“…As seen in other studies [ 10 ], C. albicans and Aspergillus spp. were the most commonly isolated fungal from SOM specimens.…”

Isolation and antimicrobial drug susceptibility pattern of bacterial pathogens from pediatric patients with otitis media in selected health institutions, Addis Ababa, Ethiopia: a prospective cross-sectional study

“…S. aureus isolates were resistant to gentamycin in the current study in contrast to other studies which have observed > 80% sensitivity [ 26 , 27 , 42 ]. P. aeruginosa isolates were relatively susceptible (63%) to Ciprofloxacin, > 80% susceptible to Amoxicillin -Clavulanic acid, Tobramycin, Ceftazidime and Cefuroxime comparable with another study [ 20 , 43 ]. However, a study in Ethiopia by Wasihun and Zemene, 2015 [ 35 ] and Pakistan by Khalil et al [ 24 ] have shown high resistance of P. aeruginosa to Amoxicillin -Clavulanic acid.…”