Aerial parts of Enicostemma littorale Blume serve as antipyretic and antacid: in vivo and in vitro evaluations

Pharmacognosy of Enicostemma littorale: A review

“…littorale is traditionally used in India as a stomachic, bitter tonic, carminative to reduce fever [6] and as a tonic for appetite loss [7] . In Indian ayurvedic medicine, E. littorale is taken in combination with other herbs, especially for diabetes.…”

“…The presence of minerals like iron, potassium, sodium, calcium, magnesium, silica, phosphate, chloride, sulphate and carbonate were estimated in the qualitative analysis of ash. Natarajan and Prasad reported the presence of five alkaloids, two sterols and volatile oil [7] . Betulin, a triterpene sapogenin was also isolated by earlier workers [16] .…”

In-vitro antiulcer activities of petal extract of Crocus sativus var. cashmerianus

“…Antacids act by neutralizing gastric acid and thereby reduce the gastric pH [9]. The acid neutralizing capacity of an antacid is the amount of per gm of acid that it can neutralize [5,10]. In ANC, results showed concentration dependent reduction was found in acid neutralizing capacity vs. per gm of antacid used.…”

“…Then 30 ml of 1N HCl was added into standard and test preparation and stirred for 15 minutes, 2-3 drops of phenolphthalein solution was added and mixed. The excess HCl was immediately titrated with 0.5N Sodium hydroxide solution drop wise until a pink color is appeared [5].…”

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“…To the standard and test preparation, the 30ml of 1.0 N HCl was added and stirred for 15 minutes after that phenolphthalein was added and mixed. With 0.5N Sodium hydroxide, the excess HCl was immediately titrated until the pink colour is attained 15 . The moles of acid neutralized is calculated by, Moles of acid neutralized = (vol.…”