Adverse Reactions to Iodinated Radiographic Contrast Media

Cohan, Richard H.; Ellis, James H.

doi:10.1007/978-3-642-59814-2_11

Cited by 8 publications

(11 citation statements)

References 110 publications

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“…If an allergy is suspected then pretreatment with antihistamines and corticosteroids should be considered [72, 73] or gadolinium should be used as an alternative [74]. These reactions are highly unusual in extravascular procedures [75]. …”

Section: Complicationsmentioning

confidence: 99%

Complications and pitfalls of lumbar interlaminar and transforaminal epidural injections

Goodman

Posecion

Mallempati

et al. 2008

Curr Rev Musculoskelet Med

145

114

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Lumbar interlaminar and transforaminal epidural injections are used in the treatment of lumbar radicular pain and other lumbar spinal pain syndromes. Complications from these procedures arise from needle placement and the administration of medication. Potential risks include infection, hematoma, intravascular injection of medication, direct nerve trauma, subdural injection of medication, air embolism, disc entry, urinary retention, radiation exposure, and hypersensitivity reactions. The objective of this article is to review the complications of lumbar interlaminar and transforaminal epidural injections and discuss the potential pitfalls related to these procedures. We performed a comprehensive literature review through a Medline search for relevant case reports, clinical trials, and review articles. Complications from lumbar epidural injections are extremely rare. Most if not all complications can be avoided by careful technique with accurate needle placement, sterile precautions, and a thorough understanding of the relevant anatomy and contrast patterns on fluoroscopic imaging.

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Section: Complicationsmentioning

confidence: 99%

Complications and pitfalls of lumbar interlaminar and transforaminal epidural injections

Goodman

Posecion

Mallempati

et al. 2008

Curr Rev Musculoskelet Med

145

114

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“…Data on contrast agents included type of the agent, contrast agent concentration, and total contrast agent dose [17]. Allergic history included any history of antibiotics, or any other drug [10,18].…”

Section: Methodsmentioning

confidence: 99%

Risk factors for adverse reactions from contrast agents for computed tomography

Kobayashi

Takahashi

Ueda

et al. 2013

BMC Med Inform Decis Mak

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BackgroundSymptoms of an adverse reaction to contrast agents for computed tomography are diverse ranging, and sometimes serious. The goal of this study is to create a scoring rule to predict adverse reactions to contrast agents used in computed tomography.MethodsThis was a retrospective cohort study of all adult patients undergoing contrast enhanced CT scan for 7 years. The subjects were randomly divided into either a derivation or validation group. Baseline data and clinically relevant factors were collected from the electronic chart. Primary outcome was any acute adverse reactions to contrast media, observed for during 24 hours after administration. All potential candidate predictors were included in a forward stepwise logistic regression model. Prediction scores were assigned based on β coefficient. A receiver operating characteristic (ROC) curve was drawn, and the area under the curve (AUC) and incidence of acute adverse reactions at each point were obtained. The same process was performed in the validation group.Results36,472 patients underwent enhanced CT imaging: 20,000 patients in the derivation group and 16,472 in the validation group. A total of 409 (2.0%, 95% CI:1.9-2.3) and 347 (2.1%, 95% CI:1.9-2.3) acute adverse reactions were seen in the derivation and validation groups. Logistic regression analysis revealed that prior adverse reaction to contrast agents, urticaria, an allergic history to drugs other than contrast agents, contrast agent concentration >70%, age <50 years, and total contrast agent dose >65 g were significant predictors of an acute adverse reaction. AUC was 0.70 (95% CI:0.67-0.73) and 0.67 (95% CI:0.64-0.70) in the derivation and validation groups.ConclusionsWe suggest a prediction model consisting of six predictors for acute adverse reactions to contrast agents used in CT.

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“…Radiologists and their staff should review treatment protocols regularly (e.g., at 6-12 monthly intervals) so that each can accomplish his or her role efficiently (Gillenberger et al 1986;Bush and Swanson 1991;Emergency Cardiac Care Committee and Subcommittees 1992;Berden et al 1993;Bush et al 1993;Cohan et al 1996;Bartlett and Bynevelt 2003). Knowledge, training, and preparation are crucial for guaranteeing appropriate and effective treatment if there is an adverse contrast-related event.…”

Section: Be Preparedmentioning

confidence: 98%

Management of Acute Adverse Reactions to Contrast Media

Thomsen

2014

Medical Radiology

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Adverse Reactions to Iodinated Radiographic Contrast Media

Cited by 8 publications

References 110 publications

Complications and pitfalls of lumbar interlaminar and transforaminal epidural injections

Complications and pitfalls of lumbar interlaminar and transforaminal epidural injections

Risk factors for adverse reactions from contrast agents for computed tomography

Management of Acute Adverse Reactions to Contrast Media

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