Adverse outcome of coarctation stenting in patients with Turner syndrome

Abstract

Though percutaneous treatment of aortic coarctation in TS patients is effective, it is associated with serious morbidity and mortality. These risks suggest that alternative treatment options should be carefully weighed against percutaneous stenting strategies. © 2016 Wiley Periodicals, Inc.

A sudden turner of events

“…These findings were strikingly different from those reported in 2017 by van den Hoven et al In a multicenter cohort study including 19 patients, three adverse events occurred within 30 days after the procedure, including two dissections, one leading to death. The patients were followed‐up for a further 6.5 years with two unrelated deaths . The authors concluded that stenting should be avoided in TS …”

“…Two patients developed late aortic aneurysms and no restenosis was reported, concluding that stent implantation is a safe and effective option . These findings were strikingly different from those reported in 2017 by van den Hoven et al In a multicenter cohort study including 19 patients, three adverse events occurred within 30 days after the procedure, including two dissections, one leading to death. The patients were followed‐up for a further 6.5 years with two unrelated deaths .…”

“…The patients were followed‐up for a further 6.5 years with two unrelated deaths . The authors concluded that stenting should be avoided in TS …”

“…Considering TS patients with aortic coarctation, conflicting orientations regarding surgical vs percutaneous management have been documented in the literature, enhancing the pertinence of this case report.…”

“…Congenital heart disease occurs in 50% of these patients including bicuspid aortic valve, aortic coarctation, and an aortopathy . Histologically, aortic wall abnormalities including cystic medial wall necrosis and changes in vascular smooth muscle cells, elastin or collagen fibers, lead to a higher risk of dissection, approximately 40 per 100 000 person‐years compared with 6 per 100 000 person‐years in the general population …”